Atlas of nascent RNA transcripts reveals tissue-specific enhancer to gene linkages

Atlas of nascent RNA transcripts reveals tissue-specific enhancer to gene linkages

Abstract Gene transcription is controlled and modulated by regulatory regions, including enhancers and promoters. These regions are abundant in non-coding bidirectional transcription that results in generally unstable RNA. Using nascent RNA transcription data across hundreds of human samples, we ide...

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Bibliographic Details
Main Authors: Rutendo F. Sigauke, Lynn Sanford, Zachary L. Maas, Taylor Jones, Jacob T. Stanley, Hope A. Townsend, Mary A. Allen, Robin D. Dowell
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
Nascent RNA sequencing
Bidirectional transcription
Enhancer RNA
Online Access:https://doi.org/10.1186/s12864-025-11568-z
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