Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report

Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disorder that affects the skin, eyes and peripheral nervous system. It is rarely associated with glaucoma, especially in pediatric patients. We herein report an unusual case of corneal degeneration in a child with NF1, characterized by peri...

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Main Authors: Ling Ying Ge, Xin Tian, Han Mu Guo, Xue Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1469969/full
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author Ling Ying Ge
Xin Tian
Han Mu Guo
Xue Yin
author_facet Ling Ying Ge
Xin Tian
Han Mu Guo
Xue Yin
author_sort Ling Ying Ge
collection DOAJ
description Neurofibromatosis type 1 (NF1) is a rare autosomal dominant disorder that affects the skin, eyes and peripheral nervous system. It is rarely associated with glaucoma, especially in pediatric patients. We herein report an unusual case of corneal degeneration in a child with NF1, characterized by peripheral corneal leukoma and a membrane under Descemet’s membrane. This finding offers new insights for the ophthalmic diagnosis of NF1.
format Article
id doaj-art-6d2a6b0bcc0e49b8ae268687436d7264
institution OA Journals
issn 2234-943X
language English
publishDate 2024-11-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Oncology
spelling doaj-art-6d2a6b0bcc0e49b8ae268687436d72642025-08-20T02:27:43ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2024-11-011410.3389/fonc.2024.14699691469969Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case reportLing Ying GeXin TianHan Mu GuoXue YinNeurofibromatosis type 1 (NF1) is a rare autosomal dominant disorder that affects the skin, eyes and peripheral nervous system. It is rarely associated with glaucoma, especially in pediatric patients. We herein report an unusual case of corneal degeneration in a child with NF1, characterized by peripheral corneal leukoma and a membrane under Descemet’s membrane. This finding offers new insights for the ophthalmic diagnosis of NF1.https://www.frontiersin.org/articles/10.3389/fonc.2024.1469969/fullneurofibromatosis type 1corneal leukomaatrial angle dysplasiasecondary glaucomachildren
spellingShingle Ling Ying Ge
Xin Tian
Han Mu Guo
Xue Yin
Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
Frontiers in Oncology
neurofibromatosis type 1
corneal leukoma
atrial angle dysplasia
secondary glaucoma
children
title Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
title_full Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
title_fullStr Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
title_full_unstemmed Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
title_short Secondary childhood glaucoma in neurofibromatosis type 1: an unusual corneal leukoma case report
title_sort secondary childhood glaucoma in neurofibromatosis type 1 an unusual corneal leukoma case report
topic neurofibromatosis type 1
corneal leukoma
atrial angle dysplasia
secondary glaucoma
children
url https://www.frontiersin.org/articles/10.3389/fonc.2024.1469969/full
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AT xintian secondarychildhoodglaucomainneurofibromatosistype1anunusualcornealleukomacasereport
AT hanmuguo secondarychildhoodglaucomainneurofibromatosistype1anunusualcornealleukomacasereport
AT xueyin secondarychildhoodglaucomainneurofibromatosistype1anunusualcornealleukomacasereport