Bicarbonate-mediated proton transfer requires cations
Abstract Near-neutral HCO3 – aqueous solution plays an essential role in respiratory, mineralization and catalysis, yet the interconversion between hydrated CO2, HCO3 – and CO3 2– and the associated proton transfer under such proton-deficient conditions remain uncovered. Here we reveal that cation e...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-53526-5 |
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| _version_ | 1850203557922340864 |
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| author | Qianbao Wu Na Yang Mengjun Xiao Wei Wang Chunhua Cui |
| author_facet | Qianbao Wu Na Yang Mengjun Xiao Wei Wang Chunhua Cui |
| author_sort | Qianbao Wu |
| collection | DOAJ |
| description | Abstract Near-neutral HCO3 – aqueous solution plays an essential role in respiratory, mineralization and catalysis, yet the interconversion between hydrated CO2, HCO3 – and CO3 2– and the associated proton transfer under such proton-deficient conditions remain uncovered. Here we reveal that cation enables HCO3 – to self-dissociate into OH– and CO2 through a pH-independent process, where CO2 hydration and subsequent proton transfer in acid-base reactions lead to the overall exchange of oxygen isotopes between HCO3 – and H2O tracked by oxygen isotope-labeled Raman spectroscopy. Isolating HCO3 – from cations with crown ether impedes HCO3 – dissociation and the following reactions. Further molecular dynamics simulations demonstrate that the interplay between HCO3 – and hydrated cations drives HCO3 – dissociation. This study suggests a natural proton channel upon coupling HCO3 – with cations. |
| format | Article |
| id | doaj-art-6d2495ce47234653833daa5bbb05c481 |
| institution | OA Journals |
| issn | 2041-1723 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj-art-6d2495ce47234653833daa5bbb05c4812025-08-20T02:11:29ZengNature PortfolioNature Communications2041-17232024-10-011511810.1038/s41467-024-53526-5Bicarbonate-mediated proton transfer requires cationsQianbao Wu0Na Yang1Mengjun Xiao2Wei Wang3Chunhua Cui4Molecular Electrochemistry Laboratory, Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of ChinaSchool of Materials and Energy, University of Electronic Science and Technology of ChinaMolecular Electrochemistry Laboratory, Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of ChinaSchool of Materials and Energy, University of Electronic Science and Technology of ChinaMolecular Electrochemistry Laboratory, Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of ChinaAbstract Near-neutral HCO3 – aqueous solution plays an essential role in respiratory, mineralization and catalysis, yet the interconversion between hydrated CO2, HCO3 – and CO3 2– and the associated proton transfer under such proton-deficient conditions remain uncovered. Here we reveal that cation enables HCO3 – to self-dissociate into OH– and CO2 through a pH-independent process, where CO2 hydration and subsequent proton transfer in acid-base reactions lead to the overall exchange of oxygen isotopes between HCO3 – and H2O tracked by oxygen isotope-labeled Raman spectroscopy. Isolating HCO3 – from cations with crown ether impedes HCO3 – dissociation and the following reactions. Further molecular dynamics simulations demonstrate that the interplay between HCO3 – and hydrated cations drives HCO3 – dissociation. This study suggests a natural proton channel upon coupling HCO3 – with cations.https://doi.org/10.1038/s41467-024-53526-5 |
| spellingShingle | Qianbao Wu Na Yang Mengjun Xiao Wei Wang Chunhua Cui Bicarbonate-mediated proton transfer requires cations Nature Communications |
| title | Bicarbonate-mediated proton transfer requires cations |
| title_full | Bicarbonate-mediated proton transfer requires cations |
| title_fullStr | Bicarbonate-mediated proton transfer requires cations |
| title_full_unstemmed | Bicarbonate-mediated proton transfer requires cations |
| title_short | Bicarbonate-mediated proton transfer requires cations |
| title_sort | bicarbonate mediated proton transfer requires cations |
| url | https://doi.org/10.1038/s41467-024-53526-5 |
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