Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1.
Bartonella T4SS effector BepC was reported to mediate internalization of big Bartonella aggregates into host cells by modulating F-actin polymerization. After that, BepC was indicated to induce host cell fragmentation, an interesting cell phenotype that is characterized by failure of rear-end retrac...
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| Main Authors: | Chunyan Wang, Haoran Zhang, Jiaqi Fu, Meng Wang, Yuhao Cai, Tianyun Ding, Jiezhang Jiang, Jane E Koehler, Xiaoyun Liu, Congli Yuan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009065&type=printable |
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