Grem1 inhibits osteogenic differentiation of MBMSCs in OVX rats through BMP/Smad1/5 signaling pathway

Grem1 inhibits osteogenic differentiation of MBMSCs in OVX rats through BMP/Smad1/5 signaling pathway

Objective: This study aims to explore how Grem1 regulates the differentiation and signaling activity of mandibular bone marrow mesenchymal stem cells (MBMSCs), affecting their osteogenic differentiation capacity and participating in the pathophysiological mechanism of postmenopausal mandibular osteo...

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Bibliographic Details
Main Authors:	Shan-shan Yang, Min LinHu, Xiao-hua Hu, Si-si Jiang, Wen-yue Hu, Xiao-hong Yang
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Series:	Regenerative Therapy
Subjects:	Grem1 Mandibular bone marrow mesenchymal stem cells (MBMSCs) Postmenopausal mandibular osteoporosis Bone homeostasis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352320425000148
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