MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE
Nowadays conception of blood pressure (BP) variability (BPV) includes a number of indicators related to various physiological factors. All the indexes are calculated with the standard deviation (SD) or more complex formulas, including SD. BPV main varieties are considered a 24-hour BPV (measured by...
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Столичная издательская компания
2015-12-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/641 |
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| author | V. M. Gorbunov |
| author_facet | V. M. Gorbunov |
| author_sort | V. M. Gorbunov |
| collection | DOAJ |
| description | Nowadays conception of blood pressure (BP) variability (BPV) includes a number of indicators related to various physiological factors. All the indexes are calculated with the standard deviation (SD) or more complex formulas, including SD. BPV main varieties are considered a 24-hour BPV (measured by ambulatory BP monitoring – ABPM), midterm BPV (BP self-control or home BP – HBP), and long-term, visit-to-visit, BPV (traditional BP measurement or office BP – OBP). The 24-hour BPV was the main subject of study for many years. Recently significant attention has been paid to the visit-to-visit BPV assessment. Retrospective meta-analysis showed that in a cohort of patients after stroke or transient ischemic attack, this index was a strong and independent (from the average BP level) predictor of stroke. In ASCOT-BPLA study visit-to-visit systolic BPV also was a strong predictor of stroke and coronary events. Long-term BPV in patients of amlodipine/perindopril treatment group was significantly lower than this in patients of atenolol/diuretic group during the follow-up that was associated with a lower risk of cardiovascular complications. However , the concept of visit-to-visit BPV use for risk stratification and monitoring of antihypertensive therapy efficacy is associated with significant limitations (basic data is obtained in the post hoc analysis, difficulties in objective evaluation of prognostic significance of indicators, their dependence on medication adherence, etc.). The HBP self-control is a promising approach to the BPV analysis; it may be the "happy medium" between ABPM and OPB. New-designed prospective comparative studies are needed to evaluate the clinical significance of the various BPV parameters. |
| format | Article |
| id | doaj-art-6d0be12a435b4b9bae6021bc775903a7 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2015-12-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-6d0be12a435b4b9bae6021bc775903a72025-08-23T10:00:21ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-018681081810.20996/1819-6446-2012-8-6-810-818640MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSUREV. M. Gorbunov0State Research Center for Preventive MedicineNowadays conception of blood pressure (BP) variability (BPV) includes a number of indicators related to various physiological factors. All the indexes are calculated with the standard deviation (SD) or more complex formulas, including SD. BPV main varieties are considered a 24-hour BPV (measured by ambulatory BP monitoring – ABPM), midterm BPV (BP self-control or home BP – HBP), and long-term, visit-to-visit, BPV (traditional BP measurement or office BP – OBP). The 24-hour BPV was the main subject of study for many years. Recently significant attention has been paid to the visit-to-visit BPV assessment. Retrospective meta-analysis showed that in a cohort of patients after stroke or transient ischemic attack, this index was a strong and independent (from the average BP level) predictor of stroke. In ASCOT-BPLA study visit-to-visit systolic BPV also was a strong predictor of stroke and coronary events. Long-term BPV in patients of amlodipine/perindopril treatment group was significantly lower than this in patients of atenolol/diuretic group during the follow-up that was associated with a lower risk of cardiovascular complications. However , the concept of visit-to-visit BPV use for risk stratification and monitoring of antihypertensive therapy efficacy is associated with significant limitations (basic data is obtained in the post hoc analysis, difficulties in objective evaluation of prognostic significance of indicators, their dependence on medication adherence, etc.). The HBP self-control is a promising approach to the BPV analysis; it may be the "happy medium" between ABPM and OPB. New-designed prospective comparative studies are needed to evaluate the clinical significance of the various BPV parameters.https://www.rpcardio.online/jour/article/view/641arterial hypertensionblood pressure variabilityoffice blood pressureambulatory blood pressurehome blood pressure |
| spellingShingle | V. M. Gorbunov MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE Рациональная фармакотерапия в кардиологии arterial hypertension blood pressure variability office blood pressure ambulatory blood pressure home blood pressure |
| title | MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE |
| title_full | MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE |
| title_fullStr | MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE |
| title_full_unstemmed | MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE |
| title_short | MODERN VIEWS ON THE VARIABILITY OF BLOOD PRESSURE |
| title_sort | modern views on the variability of blood pressure |
| topic | arterial hypertension blood pressure variability office blood pressure ambulatory blood pressure home blood pressure |
| url | https://www.rpcardio.online/jour/article/view/641 |
| work_keys_str_mv | AT vmgorbunov modernviewsonthevariabilityofbloodpressure |