Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure

Purpose. To compare the effects of early phacoemulsification and intraocular lens implantation (phaco/IOL), delayed phaco/IOL after initial laser peripheral iridotomy (LPI), and conventional LPI alone in patients with acute primary angle-closure (PAC). Methods. Patients with acute PAC were included...

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Main Authors: Yun-Hsuan Lin, Cheng-Hsiu Wu, Shih-Ming Huang, Chen Hsieh, Henry Shen-Lih Chen, Wan-Chen Ku, Ming-Hui Sun, Wei-Wen Su
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2020/8319570
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author Yun-Hsuan Lin
Cheng-Hsiu Wu
Shih-Ming Huang
Chen Hsieh
Henry Shen-Lih Chen
Wan-Chen Ku
Ming-Hui Sun
Wei-Wen Su
author_facet Yun-Hsuan Lin
Cheng-Hsiu Wu
Shih-Ming Huang
Chen Hsieh
Henry Shen-Lih Chen
Wan-Chen Ku
Ming-Hui Sun
Wei-Wen Su
author_sort Yun-Hsuan Lin
collection DOAJ
description Purpose. To compare the effects of early phacoemulsification and intraocular lens implantation (phaco/IOL), delayed phaco/IOL after initial laser peripheral iridotomy (LPI), and conventional LPI alone in patients with acute primary angle-closure (PAC). Methods. Patients with acute PAC were included in the study, and those with secondary glaucoma, prior ocular trauma, or other ocular diseases and those who had undergone ocular surgeries previously were excluded. Patients were categorized into three groups: Group A, which underwent primary phaco/IOL after acute PAC; Group B, which underwent LPI initially after acute PAC, followed by phaco/IOL within 6 months; and Group C, which underwent LPI alone. The IOP control success at 12 months as well as changes in ocular characteristics and the number of antiglaucoma medications used after the treatment among the groups were evaluated. Results. Eighty-one eyes were included in the study: 24 eyes in Group A, 23 eyes in Group B, and 34 eyes in Group C. The linear mixed model analysis demonstrated considerable IOP control in Groups A and B. Visual acuity, anterior chamber depth (ACD), and angle width improved significantly in Groups A and B, but not in Group C. The number of antiglaucoma medications used was significantly higher in Group C than in Groups A and B. Conclusions. Patients who underwent phaco/IOL had better IOP control, improved vision, deeper ACD, and wider angle and required less antiglaucoma medications than those who underwent LPI alone. Performing phaco/IOL weeks to months after the initial LPI did not appear to adversely affect outcomes compared with those of early phaco/IOL.
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spelling doaj-art-6d0ab8682e164e1ebbb2485c67503f802025-02-03T06:05:14ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/83195708319570Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-ClosureYun-Hsuan Lin0Cheng-Hsiu Wu1Shih-Ming Huang2Chen Hsieh3Henry Shen-Lih Chen4Wan-Chen Ku5Ming-Hui Sun6Wei-Wen Su7Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung Branch, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Keelung Branch, TaiwanChang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, TaiwanChang Gung University College of Medicine, Taoyuan, TaiwanDepartment of Ophthalmology, Chang Gung Memorial Hospital, Keelung Branch, TaiwanChang Gung University College of Medicine, Taoyuan, TaiwanChang Gung University College of Medicine, Taoyuan, TaiwanPurpose. To compare the effects of early phacoemulsification and intraocular lens implantation (phaco/IOL), delayed phaco/IOL after initial laser peripheral iridotomy (LPI), and conventional LPI alone in patients with acute primary angle-closure (PAC). Methods. Patients with acute PAC were included in the study, and those with secondary glaucoma, prior ocular trauma, or other ocular diseases and those who had undergone ocular surgeries previously were excluded. Patients were categorized into three groups: Group A, which underwent primary phaco/IOL after acute PAC; Group B, which underwent LPI initially after acute PAC, followed by phaco/IOL within 6 months; and Group C, which underwent LPI alone. The IOP control success at 12 months as well as changes in ocular characteristics and the number of antiglaucoma medications used after the treatment among the groups were evaluated. Results. Eighty-one eyes were included in the study: 24 eyes in Group A, 23 eyes in Group B, and 34 eyes in Group C. The linear mixed model analysis demonstrated considerable IOP control in Groups A and B. Visual acuity, anterior chamber depth (ACD), and angle width improved significantly in Groups A and B, but not in Group C. The number of antiglaucoma medications used was significantly higher in Group C than in Groups A and B. Conclusions. Patients who underwent phaco/IOL had better IOP control, improved vision, deeper ACD, and wider angle and required less antiglaucoma medications than those who underwent LPI alone. Performing phaco/IOL weeks to months after the initial LPI did not appear to adversely affect outcomes compared with those of early phaco/IOL.http://dx.doi.org/10.1155/2020/8319570
spellingShingle Yun-Hsuan Lin
Cheng-Hsiu Wu
Shih-Ming Huang
Chen Hsieh
Henry Shen-Lih Chen
Wan-Chen Ku
Ming-Hui Sun
Wei-Wen Su
Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
Journal of Ophthalmology
title Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
title_full Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
title_fullStr Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
title_full_unstemmed Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
title_short Early versus Delayed Phacoemulsification and Intraocular Lens Implantation for Acute Primary Angle-Closure
title_sort early versus delayed phacoemulsification and intraocular lens implantation for acute primary angle closure
url http://dx.doi.org/10.1155/2020/8319570
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