Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)

Aim of investigation. To estimate frequency of flat adenomas of the large intestine in men and women of various age groups, that underwent total videocolonoscopy. To study macroscopic and morphological differences of flat adenomas in relation to locating within the large intestine.Materials and meth...

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Main Authors: S. I. Zaikin, V. V. Agadzhanyan, T. V. Levchenko, Ye. A. Pervov, P. A. Frolov
Format: Article
Language:Russian
Published: Gastro LLC 2009-02-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/1604
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author S. I. Zaikin
V. V. Agadzhanyan
T. V. Levchenko
Ye. A. Pervov
P. A. Frolov
author_facet S. I. Zaikin
V. V. Agadzhanyan
T. V. Levchenko
Ye. A. Pervov
P. A. Frolov
author_sort S. I. Zaikin
collection DOAJ
description Aim of investigation. To estimate frequency of flat adenomas of the large intestine in men and women of various age groups, that underwent total videocolonoscopy. To study macroscopic and morphological differences of flat adenomas in relation to locating within the large intestine.Materials and methods. Total colonoscopy by CF-V70L device («Olympus», Japan) after preparation by Fortrans (macrogoal) «Ipsen» company (France) was carried out in 1859 patients, inhabitants of Kuzbass region. Each patient with suspicion to structural mucosal changes underwent guided chromoscopy with 0,2% indigo carmine solution. Neoplasms, which were revealed, were subjected to biopsy by FB-24U forcipes or resection by SD-17U loop («Olympus», Japan). Results. Overall 1859 patients were investigated, in 849 cases (45,7%) 1631 adenoma has been found, 1344 (82,5%) of them were of the I type. At 176 (9,5%) patients 287 (17,5%) adenomas II of type were revealed. Flat adenomas were found most often in males in the age of 30 to 49 years at the right part of the colon, 285 (99,3%) adenomas were of the IIa type, 270 (94,1%) were &lt;10 mm in size. The majority of flat adenomas – 275 (95,8%) – had tubular structure, in 14 (4,9%) the high degree dysplasia was found. Conclusions. Flat adenomas of the large intestine – is not an infrequent disease among Kemerovo region inhabitants (it is found in 9,5 % of the patients undergoing total videocolonoscopy with chromoscopy). The risk of neoplastic transformation increases with increase of&gt;&lt;10 mm in size. The majority of flat adenomas – 275 (95,8%) – had tubular structure, in 14 (4,9%) the high degree dysplasia was found.Conclusions. Flat adenomas of the large intestine – is not an infrequent disease among Kemerovo region inhabitants (it is found in 9,5 % of the patients undergoing total videocolonoscopy with chromoscopy). The risk of neoplastic transformation increases with increase of the flat adenoma size, at the presence of central excavation and location in right part of the colon.
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issn 1382-4376
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publishDate 2009-02-01
publisher Gastro LLC
record_format Article
series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-6d0811a6cc044049994d02a527262da52025-02-10T16:14:30ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732009-02-0119166701109Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)S. I. ZaikinV. V. AgadzhanyanT. V. LevchenkoYe. A. PervovP. A. FrolovAim of investigation. To estimate frequency of flat adenomas of the large intestine in men and women of various age groups, that underwent total videocolonoscopy. To study macroscopic and morphological differences of flat adenomas in relation to locating within the large intestine.Materials and methods. Total colonoscopy by CF-V70L device («Olympus», Japan) after preparation by Fortrans (macrogoal) «Ipsen» company (France) was carried out in 1859 patients, inhabitants of Kuzbass region. Each patient with suspicion to structural mucosal changes underwent guided chromoscopy with 0,2% indigo carmine solution. Neoplasms, which were revealed, were subjected to biopsy by FB-24U forcipes or resection by SD-17U loop («Olympus», Japan). Results. Overall 1859 patients were investigated, in 849 cases (45,7%) 1631 adenoma has been found, 1344 (82,5%) of them were of the I type. At 176 (9,5%) patients 287 (17,5%) adenomas II of type were revealed. Flat adenomas were found most often in males in the age of 30 to 49 years at the right part of the colon, 285 (99,3%) adenomas were of the IIa type, 270 (94,1%) were &lt;10 mm in size. The majority of flat adenomas – 275 (95,8%) – had tubular structure, in 14 (4,9%) the high degree dysplasia was found. Conclusions. Flat adenomas of the large intestine – is not an infrequent disease among Kemerovo region inhabitants (it is found in 9,5 % of the patients undergoing total videocolonoscopy with chromoscopy). The risk of neoplastic transformation increases with increase of&gt;&lt;10 mm in size. The majority of flat adenomas – 275 (95,8%) – had tubular structure, in 14 (4,9%) the high degree dysplasia was found.Conclusions. Flat adenomas of the large intestine – is not an infrequent disease among Kemerovo region inhabitants (it is found in 9,5 % of the patients undergoing total videocolonoscopy with chromoscopy). The risk of neoplastic transformation increases with increase of the flat adenoma size, at the presence of central excavation and location in right part of the colon.https://www.gastro-j.ru/jour/article/view/1604flat adenomalarge intestinedysplasia
spellingShingle S. I. Zaikin
V. V. Agadzhanyan
T. V. Levchenko
Ye. A. Pervov
P. A. Frolov
Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
flat adenoma
large intestine
dysplasia
title Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
title_full Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
title_fullStr Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
title_full_unstemmed Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
title_short Videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine (<i>Prospective study</i>)
title_sort videocolonoscopy and chromoscopy in diagnostics of flat adenomas of the large intestine i prospective study i
topic flat adenoma
large intestine
dysplasia
url https://www.gastro-j.ru/jour/article/view/1604
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AT vvagadzhanyan videocolonoscopyandchromoscopyindiagnosticsofflatadenomasofthelargeintestineiprospectivestudyi
AT tvlevchenko videocolonoscopyandchromoscopyindiagnosticsofflatadenomasofthelargeintestineiprospectivestudyi
AT yeapervov videocolonoscopyandchromoscopyindiagnosticsofflatadenomasofthelargeintestineiprospectivestudyi
AT pafrolov videocolonoscopyandchromoscopyindiagnosticsofflatadenomasofthelargeintestineiprospectivestudyi