Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review
Isolated hyperbilirubinemia as a manifestation of alcoholic liver disease without significant liver abnormalities is seen very rarely. We report such a case where a patient with chronic alcoholism presented to the ER with acute jaundice with bilirubin of 24.8 mg/dl, predominantly conjugated in natur...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2018/9403934 |
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| author | Muhammad Rajib Hossain Ramesh Kumar Pandey Mohammad Faridul Islam Praveen Datar Vijay Gayam Pradeep Puri Thwin Malar |
| author_facet | Muhammad Rajib Hossain Ramesh Kumar Pandey Mohammad Faridul Islam Praveen Datar Vijay Gayam Pradeep Puri Thwin Malar |
| author_sort | Muhammad Rajib Hossain |
| collection | DOAJ |
| description | Isolated hyperbilirubinemia as a manifestation of alcoholic liver disease without significant liver abnormalities is seen very rarely. We report such a case where a patient with chronic alcoholism presented to the ER with acute jaundice with bilirubin of 24.8 mg/dl, predominantly conjugated in nature along with mild elevation of AST (76 IU/L). There were no other abnormalities of the liver function. The patient underwent extensive laboratory and imaging tests that excluded extrahepatic cholestasis, viral and autoimmune hepatitis, ischemic hepatitis, and so forth. Liver biopsy excluded hemochromatosis, dysplasia, or malignancy and other differentials. Bilirubin gradually trended down to 7.3 mg/dl when alcohol consumption was stopped. |
| format | Article |
| id | doaj-art-6d01d94a39064c00a47c00f70ce5da45 |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-6d01d94a39064c00a47c00f70ce5da452025-08-20T03:34:10ZengWileyCase Reports in Hepatology2090-65872090-65952018-01-01201810.1155/2018/94039349403934Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature ReviewMuhammad Rajib Hossain0Ramesh Kumar Pandey1Mohammad Faridul Islam2Praveen Datar3Vijay Gayam4Pradeep Puri5Thwin Malar6Department of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USADepartment of Medicine, Interfaith Medical Center, Brooklyn, NY, USAIsolated hyperbilirubinemia as a manifestation of alcoholic liver disease without significant liver abnormalities is seen very rarely. We report such a case where a patient with chronic alcoholism presented to the ER with acute jaundice with bilirubin of 24.8 mg/dl, predominantly conjugated in nature along with mild elevation of AST (76 IU/L). There were no other abnormalities of the liver function. The patient underwent extensive laboratory and imaging tests that excluded extrahepatic cholestasis, viral and autoimmune hepatitis, ischemic hepatitis, and so forth. Liver biopsy excluded hemochromatosis, dysplasia, or malignancy and other differentials. Bilirubin gradually trended down to 7.3 mg/dl when alcohol consumption was stopped.http://dx.doi.org/10.1155/2018/9403934 |
| spellingShingle | Muhammad Rajib Hossain Ramesh Kumar Pandey Mohammad Faridul Islam Praveen Datar Vijay Gayam Pradeep Puri Thwin Malar Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review Case Reports in Hepatology |
| title | Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review |
| title_full | Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review |
| title_fullStr | Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review |
| title_full_unstemmed | Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review |
| title_short | Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review |
| title_sort | acute isolated hyperbilirubinemia as a presentation of alcoholic liver disease a case report and literature review |
| url | http://dx.doi.org/10.1155/2018/9403934 |
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