The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis
Objective: to estimate the high and very high Frax® 10-year probabilities of fractures in patients with systemic sclerosis (SSc) to assess the need for anti-osteoporotic treatment.Patients and methods. The investigation enrolled 136 SSc patients (110 women and 26 men; mean age, 59.3±7.5 years). The...
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| Format: | Article |
| Language: | Russian |
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IMA-PRESS LLC
2021-02-01
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| Series: | Современная ревматология |
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| Online Access: | https://mrj.ima-press.net/mrj/article/view/1097 |
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| author | A. О. Efremova N. V. Toroptsova O. V. Dobrovolskaya N. V. Demin O. A. Nikitinskaya |
| author_facet | A. О. Efremova N. V. Toroptsova O. V. Dobrovolskaya N. V. Demin O. A. Nikitinskaya |
| author_sort | A. О. Efremova |
| collection | DOAJ |
| description | Objective: to estimate the high and very high Frax® 10-year probabilities of fractures in patients with systemic sclerosis (SSc) to assess the need for anti-osteoporotic treatment.Patients and methods. The investigation enrolled 136 SSc patients (110 women and 26 men; mean age, 59.3±7.5 years). The patients underwent a questionnaire survey, by calculating the risk of major fractures with the FRAX® algorithm and dual-energy X-ray densitometry (DXA) of the lumbar spine and proximal femur.Results and discussion. There was a very high risk of fractures in 41.2% of the examinees, a high risk in 10.3%, and a low risk in 48.5%. Osteoporosis (OP) in at least one area was detected in 41.2% of the patients. Among the persons with a low risk of fractures, OP was diagnosed in 18.2%, whereas 10.6% had a history of fractures. A total of 65.4% of SSc patients needed anti-osteoporotic treatment.Conclusion. According to the comprehensive assessment, OP treatment and fracture prevention were indicated for 65.4% of SSc patients. The FRAX® algorithm is less informative in males who need therapy than in females. |
| format | Article |
| id | doaj-art-6cf568eb173b4b3e8b744df0de14fb8d |
| institution | DOAJ |
| issn | 1996-7012 2310-158X |
| language | Russian |
| publishDate | 2021-02-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj-art-6cf568eb173b4b3e8b744df0de14fb8d2025-08-20T03:01:22ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-02-01151323710.14412/1996-7012-2021-1-32-372320The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosisA. О. Efremova0N. V. Toroptsova1O. V. Dobrovolskaya2N. V. Demin3O. A. Nikitinskaya4V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyObjective: to estimate the high and very high Frax® 10-year probabilities of fractures in patients with systemic sclerosis (SSc) to assess the need for anti-osteoporotic treatment.Patients and methods. The investigation enrolled 136 SSc patients (110 women and 26 men; mean age, 59.3±7.5 years). The patients underwent a questionnaire survey, by calculating the risk of major fractures with the FRAX® algorithm and dual-energy X-ray densitometry (DXA) of the lumbar spine and proximal femur.Results and discussion. There was a very high risk of fractures in 41.2% of the examinees, a high risk in 10.3%, and a low risk in 48.5%. Osteoporosis (OP) in at least one area was detected in 41.2% of the patients. Among the persons with a low risk of fractures, OP was diagnosed in 18.2%, whereas 10.6% had a history of fractures. A total of 65.4% of SSc patients needed anti-osteoporotic treatment.Conclusion. According to the comprehensive assessment, OP treatment and fracture prevention were indicated for 65.4% of SSc patients. The FRAX® algorithm is less informative in males who need therapy than in females.https://mrj.ima-press.net/mrj/article/view/1097systemic sclerosisosteoporosisfrax®osteoporotic fracturerisk for fracture |
| spellingShingle | A. О. Efremova N. V. Toroptsova O. V. Dobrovolskaya N. V. Demin O. A. Nikitinskaya The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis Современная ревматология systemic sclerosis osteoporosis frax® osteoporotic fracture risk for fracture |
| title | The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis |
| title_full | The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis |
| title_fullStr | The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis |
| title_full_unstemmed | The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis |
| title_short | The risk of fractures and the need for anti-osteoporotic treatment in patients with systemic sclerosis |
| title_sort | risk of fractures and the need for anti osteoporotic treatment in patients with systemic sclerosis |
| topic | systemic sclerosis osteoporosis frax® osteoporotic fracture risk for fracture |
| url | https://mrj.ima-press.net/mrj/article/view/1097 |
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