ApoE [−/−] CA1-overexpressing knock-in mice aggravated atherosclerosis by increasing M1 macrophages
Background: Carbonic anhydrase I (CA1) has been reported to be a diagnostic and therapeutic target for atherosclerosis (AS). This study aimed to verify the essential role of CA1 in AS progression in CA1-overexpressing mice. Methods: A ApoE [−/−] CA1-overexpressing knock-in mouse model was constructe...
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| Main Authors: | Jinbao Zong, Changyuan Wang, Hongji Zhou, Yu Song, Kehua Fang, Xiaotian Chang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Atherosclerosis Plus |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667089525000070 |
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