ApoE [−/−] CA1-overexpressing knock-in mice aggravated atherosclerosis by increasing M1 macrophages

Background: Carbonic anhydrase I (CA1) has been reported to be a diagnostic and therapeutic target for atherosclerosis (AS). This study aimed to verify the essential role of CA1 in AS progression in CA1-overexpressing mice. Methods: A ApoE [−/−] CA1-overexpressing knock-in mouse model was constructe...

Full description

Saved in:
Bibliographic Details
Main Authors: Jinbao Zong, Changyuan Wang, Hongji Zhou, Yu Song, Kehua Fang, Xiaotian Chang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Atherosclerosis Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667089525000070
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items