A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis

Objective: To evaluate newly diagnosed vernal keratoconjunctivitis patients for their symptomatology, refractive errors and presence of dry eye disease along with its severity. Methods: A cross-sectional study was conducted after approval from the institutional ethics committee, among 100 patients o...

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Main Authors: Sanjeev Verma, Urmi Midya, Snehal Kedawat
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:TNOA Journal of Ophthalmic Science and Research
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Online Access:https://journals.lww.com/10.4103/tjosr.tjosr_95_22
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author Sanjeev Verma
Urmi Midya
Snehal Kedawat
author_facet Sanjeev Verma
Urmi Midya
Snehal Kedawat
author_sort Sanjeev Verma
collection DOAJ
description Objective: To evaluate newly diagnosed vernal keratoconjunctivitis patients for their symptomatology, refractive errors and presence of dry eye disease along with its severity. Methods: A cross-sectional study was conducted after approval from the institutional ethics committee, among 100 patients of vernal keratoconjunctivitis, according to the inclusion and exclusion criteria. After obtaining informed consent, visual acuity and refraction, tear film break-up time, corneal fluorescein staining and Schirmer test (I and II) were performed. An ocular surface disease index questionnaire was filled out for symptomatic evaluation and was also graded on the basis of their ocular findings. The results were analysed by SPSS software. Results: In our study, the most common symptoms experienced were itching (87%) and redness (79%). Dry eye symptoms were present in 43% of patients with an ocular surface disease index (OSDI) mean score of 11.3 ± 4.67. Out of 100 patients, 45 patients had mild findings and 55 patients had moderate findings of VKC. The mean value of tear film break-up time (TBUT) was 8.15 ± 4.47 (P: 0.539), that of corneal fluorescein staining was 4.18 ± 3.4 (P: 0.885) and those of Schirmer’s test I and II were 13.4 ± 5.9 mm (P: 0.288) and 12.95 ± 5.8 mm (P: 0.615), respectively. Myopia was found to be the most common refractive error (35%) followed by hypermetropia (30%) and astigmatism (10%). Conclusion: The results concluded that patients of VKC showed a mild-to-moderate disease and are associated with dry eye having the values of TBUT, corneal staining and Schirmer test, proving the association. Refractive errors are not present in all patients of VKC but have a positive association with increasing severity of the disease.
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spelling doaj-art-6cf36dc270f64df58c579da7aae1c75b2025-01-16T07:07:24ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362024-12-0162445445810.4103/tjosr.tjosr_95_22A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal KeratoconjunctivitisSanjeev VermaUrmi MidyaSnehal KedawatObjective: To evaluate newly diagnosed vernal keratoconjunctivitis patients for their symptomatology, refractive errors and presence of dry eye disease along with its severity. Methods: A cross-sectional study was conducted after approval from the institutional ethics committee, among 100 patients of vernal keratoconjunctivitis, according to the inclusion and exclusion criteria. After obtaining informed consent, visual acuity and refraction, tear film break-up time, corneal fluorescein staining and Schirmer test (I and II) were performed. An ocular surface disease index questionnaire was filled out for symptomatic evaluation and was also graded on the basis of their ocular findings. The results were analysed by SPSS software. Results: In our study, the most common symptoms experienced were itching (87%) and redness (79%). Dry eye symptoms were present in 43% of patients with an ocular surface disease index (OSDI) mean score of 11.3 ± 4.67. Out of 100 patients, 45 patients had mild findings and 55 patients had moderate findings of VKC. The mean value of tear film break-up time (TBUT) was 8.15 ± 4.47 (P: 0.539), that of corneal fluorescein staining was 4.18 ± 3.4 (P: 0.885) and those of Schirmer’s test I and II were 13.4 ± 5.9 mm (P: 0.288) and 12.95 ± 5.8 mm (P: 0.615), respectively. Myopia was found to be the most common refractive error (35%) followed by hypermetropia (30%) and astigmatism (10%). Conclusion: The results concluded that patients of VKC showed a mild-to-moderate disease and are associated with dry eye having the values of TBUT, corneal staining and Schirmer test, proving the association. Refractive errors are not present in all patients of VKC but have a positive association with increasing severity of the disease.https://journals.lww.com/10.4103/tjosr.tjosr_95_22corneal fluorescein stainingdry eyerefractive errorschirmer testtear film break-up timevernal keratoconjunctivitis
spellingShingle Sanjeev Verma
Urmi Midya
Snehal Kedawat
A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
TNOA Journal of Ophthalmic Science and Research
corneal fluorescein staining
dry eye
refractive error
schirmer test
tear film break-up time
vernal keratoconjunctivitis
title A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
title_full A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
title_fullStr A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
title_full_unstemmed A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
title_short A Cross-Sectional Study to Evaluate the Refractive Status and Dry Eye Disease in Cases of Vernal Keratoconjunctivitis
title_sort cross sectional study to evaluate the refractive status and dry eye disease in cases of vernal keratoconjunctivitis
topic corneal fluorescein staining
dry eye
refractive error
schirmer test
tear film break-up time
vernal keratoconjunctivitis
url https://journals.lww.com/10.4103/tjosr.tjosr_95_22
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