Promising Biomarkers in Renal Cell Carcinoma
Renal cell carcinoma (RCC) incidence has been increasing in recent years, and it now represents the sixth most common cancer diagnosis in men and the tenth in women. Although this is partly due to increased detection of incidental small renal masses on unrelated imaging, advanced RCC continues to be...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Société Internationale d’Urologie Journal |
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| Online Access: | https://siuj.org/index.php/siuj/article/view/92/16 |
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| author | Jada Kapoor, Francesco Claps, Carmen Mir, Joseph Ischia |
| author_facet | Jada Kapoor, Francesco Claps, Carmen Mir, Joseph Ischia |
| author_sort | Jada Kapoor, Francesco Claps, Carmen Mir, Joseph Ischia |
| collection | DOAJ |
| description | Renal cell carcinoma (RCC) incidence has been increasing in recent years, and it now represents the sixth most common cancer diagnosis in men and the tenth in women. Although this is partly due to increased detection of incidental small renal masses on unrelated imaging, advanced RCC continues to be diagnosed in a significant portion of patients, with more than 15% presenting with distant metastases. Biomarkers can be a cost-effective tool to identify high-risk patients and institute appropriate individualised therapies. While the literature in this field is nascent, this paper focuses on several biomarkers that have been extensively investigated in the diagnosis and prognosis of RCC, as well as in predicting its response to treatments, particularly the newer immuno-oncology drugs. |
| format | Article |
| id | doaj-art-6ceb9b245e2c43fa8ee7bc2d20782ade |
| institution | OA Journals |
| issn | 2563-6499 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Société Internationale d’Urologie Journal |
| spelling | doaj-art-6ceb9b245e2c43fa8ee7bc2d20782ade2025-08-20T01:57:11ZengMDPI AGSociété Internationale d’Urologie Journal2563-64992021-01-0121435210.48083/TNGM4076Promising Biomarkers in Renal Cell CarcinomaJada Kapoor, Francesco Claps, Carmen Mir, Joseph IschiaRenal cell carcinoma (RCC) incidence has been increasing in recent years, and it now represents the sixth most common cancer diagnosis in men and the tenth in women. Although this is partly due to increased detection of incidental small renal masses on unrelated imaging, advanced RCC continues to be diagnosed in a significant portion of patients, with more than 15% presenting with distant metastases. Biomarkers can be a cost-effective tool to identify high-risk patients and institute appropriate individualised therapies. While the literature in this field is nascent, this paper focuses on several biomarkers that have been extensively investigated in the diagnosis and prognosis of RCC, as well as in predicting its response to treatments, particularly the newer immuno-oncology drugs.https://siuj.org/index.php/siuj/article/view/92/16biomarkerskidney cancerdiagnosisprognosis |
| spellingShingle | Jada Kapoor, Francesco Claps, Carmen Mir, Joseph Ischia Promising Biomarkers in Renal Cell Carcinoma Société Internationale d’Urologie Journal biomarkers kidney cancer diagnosis prognosis |
| title | Promising Biomarkers in Renal Cell Carcinoma |
| title_full | Promising Biomarkers in Renal Cell Carcinoma |
| title_fullStr | Promising Biomarkers in Renal Cell Carcinoma |
| title_full_unstemmed | Promising Biomarkers in Renal Cell Carcinoma |
| title_short | Promising Biomarkers in Renal Cell Carcinoma |
| title_sort | promising biomarkers in renal cell carcinoma |
| topic | biomarkers kidney cancer diagnosis prognosis |
| url | https://siuj.org/index.php/siuj/article/view/92/16 |
| work_keys_str_mv | AT jadakapoorfrancescoclapscarmenmirjosephischia promisingbiomarkersinrenalcellcarcinoma |