Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing
Abstract This study aims to develop a composite hydrogel consisting of nano silver (Ag) and graphene oxide (GO) for use as a skin wound dressing. We prepared nanosilver/graphene oxide composite hydrogels by incorporating nanosilver and graphene oxide into kaolin-reinforced, gelatin-based hydrogels....
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-04-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-93310-z |
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| author | Yang Liu Liu Wang Dawei Wen Zhonghua Deng Zhifang Wu Sijin Li Yongfeng Li |
| author_facet | Yang Liu Liu Wang Dawei Wen Zhonghua Deng Zhifang Wu Sijin Li Yongfeng Li |
| author_sort | Yang Liu |
| collection | DOAJ |
| description | Abstract This study aims to develop a composite hydrogel consisting of nano silver (Ag) and graphene oxide (GO) for use as a skin wound dressing. We prepared nanosilver/graphene oxide composite hydrogels by incorporating nanosilver and graphene oxide into kaolin-reinforced, gelatin-based hydrogels. Tests were conducted on the hydrogel’s water vapor permeability, mechanical properties, infrared warming performance and bacteriostatic properties under infrared light. The results indicated that kaolin enhanced the water vapor permeability and mechanical properties of the gelatin-based hydrogels. Moreover, the maximum fracture stress and strain of the hydrogel were elevated to 51.16 kPa and 1152.78% by GO, respectively. Furthermore, the modified Ag/GO hydrogels exhibited superior photothermal conversion and infrared bacteriostatic properties. This research offers valuable insights for the clinical repair of wounds and the design of new skin wound dressings, making these materials promising for such applications. |
| format | Article |
| id | doaj-art-6ce3fa3b29cd4a98805f3613cf7cd64c |
| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-6ce3fa3b29cd4a98805f3613cf7cd64c2025-08-20T02:12:01ZengNature PortfolioScientific Reports2045-23222025-04-0115111410.1038/s41598-025-93310-zPreparation and characterization of nano-silver/graphene oxide antibacterial skin dressingYang Liu0Liu Wang1Dawei Wen2Zhonghua Deng3Zhifang Wu4Sijin Li5Yongfeng Li6Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical UniversityCollege of Artificial Intelligence, Taiyuan University of TechnologyCollege of Artificial Intelligence, Taiyuan University of TechnologyCollege of Artificial Intelligence, Taiyuan University of TechnologyDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical UniversityDepartment of Nuclear Medicine, First Hospital of Shanxi Medical University, Shanxi Medical UniversityCollege of Artificial Intelligence, Taiyuan University of TechnologyAbstract This study aims to develop a composite hydrogel consisting of nano silver (Ag) and graphene oxide (GO) for use as a skin wound dressing. We prepared nanosilver/graphene oxide composite hydrogels by incorporating nanosilver and graphene oxide into kaolin-reinforced, gelatin-based hydrogels. Tests were conducted on the hydrogel’s water vapor permeability, mechanical properties, infrared warming performance and bacteriostatic properties under infrared light. The results indicated that kaolin enhanced the water vapor permeability and mechanical properties of the gelatin-based hydrogels. Moreover, the maximum fracture stress and strain of the hydrogel were elevated to 51.16 kPa and 1152.78% by GO, respectively. Furthermore, the modified Ag/GO hydrogels exhibited superior photothermal conversion and infrared bacteriostatic properties. This research offers valuable insights for the clinical repair of wounds and the design of new skin wound dressings, making these materials promising for such applications.https://doi.org/10.1038/s41598-025-93310-zSkin wound dressingComposite hydrogelGraphene oxideNano silver |
| spellingShingle | Yang Liu Liu Wang Dawei Wen Zhonghua Deng Zhifang Wu Sijin Li Yongfeng Li Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing Scientific Reports Skin wound dressing Composite hydrogel Graphene oxide Nano silver |
| title | Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing |
| title_full | Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing |
| title_fullStr | Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing |
| title_full_unstemmed | Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing |
| title_short | Preparation and characterization of nano-silver/graphene oxide antibacterial skin dressing |
| title_sort | preparation and characterization of nano silver graphene oxide antibacterial skin dressing |
| topic | Skin wound dressing Composite hydrogel Graphene oxide Nano silver |
| url | https://doi.org/10.1038/s41598-025-93310-z |
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