Increased CCR7loPD-1hiCXCR5+CD4+ T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection

Increased CCR7loPD-1hiCXCR5+CD4+ T Cells in Peripheral Blood Mononuclear Cells Are Correlated with Immune Activation in Patients with Chronic HBV Infection

T follicular helper cells (Tfh cells) affect essential immune pathogenesis in chronic hepatitis B virus (HBV) infection. The CCR7loPD-1hi Tfh subset has a partial Tfh effector phenotype and is associated with active Tfh differentiation, whereas the CCR7hiPD-1lo Tfh subset is a resting phenotype. We...

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Bibliographic Details
Main Authors:	Ya-Xin Huang, Qi-Yi Zhao, Li-Li Wu, Dong-Ying Xie, Zhi-Liang Gao, Hong Deng
Format:	Article
Language:	English
Published:	Wiley 2018-01-01
Series:	Canadian Journal of Gastroenterology and Hepatology
Online Access:	http://dx.doi.org/10.1155/2018/1020925
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