Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event
Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently, there are two widely accepted antidotes: sodi...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/217951 |
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| _version_ | 1849413268524761088 |
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| author | Andrew Meillier Cara Heller |
| author_facet | Andrew Meillier Cara Heller |
| author_sort | Andrew Meillier |
| collection | DOAJ |
| description | Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently, there are two widely accepted antidotes: sodium thiosulfate and hydroxocobalamin. These treatments act on different components of cyanide’s metabolism. Here, we present two cases resulting from the same source of cyanide poisoning and the use of both antidotes separately used with differing outcomes. |
| format | Article |
| id | doaj-art-6cd74a13e15f4e2aafb1e19521f908a7 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-6cd74a13e15f4e2aafb1e19521f908a72025-08-20T03:34:10ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/217951217951Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure EventAndrew Meillier0Cara Heller1Department of Medicine, Temple University Hospital, Philadelphia, PA 19140, USADepartment of Medicine, Temple University Hospital, Philadelphia, PA 19140, USACyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently, there are two widely accepted antidotes: sodium thiosulfate and hydroxocobalamin. These treatments act on different components of cyanide’s metabolism. Here, we present two cases resulting from the same source of cyanide poisoning and the use of both antidotes separately used with differing outcomes.http://dx.doi.org/10.1155/2015/217951 |
| spellingShingle | Andrew Meillier Cara Heller Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event Case Reports in Medicine |
| title | Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event |
| title_full | Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event |
| title_fullStr | Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event |
| title_full_unstemmed | Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event |
| title_short | Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event |
| title_sort | acute cyanide poisoning hydroxocobalamin and sodium thiosulfate treatments with two outcomes following one exposure event |
| url | http://dx.doi.org/10.1155/2015/217951 |
| work_keys_str_mv | AT andrewmeillier acutecyanidepoisoninghydroxocobalaminandsodiumthiosulfatetreatmentswithtwooutcomesfollowingoneexposureevent AT caraheller acutecyanidepoisoninghydroxocobalaminandsodiumthiosulfatetreatmentswithtwooutcomesfollowingoneexposureevent |