Current Concepts about the Etiology of Dry Eye Syndrome

The revolution in understanding the etiology and clinical manifestations of the disruption of the tearing process and the development of dry eye syndrome (CVS) has occurred in last 20–30 years. It has been established that the loss of the tear film homeostasis can occur not only because of a violati...

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Main Authors: V. N. Trubilin, E. G. Polunina, D. V. Angelova, V. V. Kurenkov, S. G. Kapkova, K. V. Chinenova, M. E. Konovalov, M. D. Pozharitsky
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2019-06-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/962
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author V. N. Trubilin
E. G. Polunina
D. V. Angelova
V. V. Kurenkov
S. G. Kapkova
K. V. Chinenova
M. E. Konovalov
M. D. Pozharitsky
author_facet V. N. Trubilin
E. G. Polunina
D. V. Angelova
V. V. Kurenkov
S. G. Kapkova
K. V. Chinenova
M. E. Konovalov
M. D. Pozharitsky
author_sort V. N. Trubilin
collection DOAJ
description The revolution in understanding the etiology and clinical manifestations of the disruption of the tearing process and the development of dry eye syndrome (CVS) has occurred in last 20–30 years. It has been established that the loss of the tear film homeostasis can occur not only because of a violation of systemic and autoimmune disorders, but also as a result of a blinking disorder and distribution of the tear film over the ocular surface. Therefore, new pathogenetic disease development mechanisms have been identified. The prevalence of diseases of the ocular surface and CVD in recent years has increased significantly. It is mostly caused not only by scientific discoveries in the field of understanding, for example, the etiological and pathophysiological role of the neurosensory mechanism of development of CVS. An important aspect is the emergence of new risk factors that potentiate the development of ocular surface diseases and CVL. These factors include the use of various drugs — antidepressants, antihistamines, hormone therapy, and others; instillation of eye drops — antiglaucoma drugs, etc., as well as the appearance of little-studied factors such as cosmetology procedures (eyelids tattooing, eyelash extensions, botulinum toxin injections for aesthetic purposes, etc.). They are carried out in proximate close to the eye and eyelids, causing multiple pathological reaction. The experience of observing patients, literature data, and the conducted study have showed that various cosmetological effects in the periorbital zone, whose popularity has increased in recent years, may cause the appearance of iatrogenic dry eye syndrome. The following most vivid clinical examples will help, encountered in our practice, to illustrate the data presented. Collecting the anamnesis, it is necessary to identify the presence of risk factors for the development of diseases of the ocular surface and CVD, to eliminate them, if possible, and to carry out adequate pathogenically based therapy.
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spelling doaj-art-6cd746d7f1a1414faa44e5a8451af6bd2025-08-20T02:56:15ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452019-06-0116223624310.18008/1816-5095-2019-2-236-243545Current Concepts about the Etiology of Dry Eye SyndromeV. N. Trubilin0E. G. Polunina1D. V. Angelova2V. V. Kurenkov3S. G. Kapkova4K. V. Chinenova5M. E. Konovalov6M. D. Pozharitsky7Academy of postgraduate education under FSBU FSCC of FMBA of RussiaAcademy of postgraduate education under FSBU FSCC of FMBA of RussiaResearch Institute of Eye DiseasesOphthalmology Clinic of Dr. KurenkovAcademy of postgraduate education under FSBU FSCC of FMBA of RussiaOphthalmology Clinic of Dr. KurenkovKonovalov eye centerAcademy of postgraduate education under FSBU FSCC of FMBA of RussiaThe revolution in understanding the etiology and clinical manifestations of the disruption of the tearing process and the development of dry eye syndrome (CVS) has occurred in last 20–30 years. It has been established that the loss of the tear film homeostasis can occur not only because of a violation of systemic and autoimmune disorders, but also as a result of a blinking disorder and distribution of the tear film over the ocular surface. Therefore, new pathogenetic disease development mechanisms have been identified. The prevalence of diseases of the ocular surface and CVD in recent years has increased significantly. It is mostly caused not only by scientific discoveries in the field of understanding, for example, the etiological and pathophysiological role of the neurosensory mechanism of development of CVS. An important aspect is the emergence of new risk factors that potentiate the development of ocular surface diseases and CVL. These factors include the use of various drugs — antidepressants, antihistamines, hormone therapy, and others; instillation of eye drops — antiglaucoma drugs, etc., as well as the appearance of little-studied factors such as cosmetology procedures (eyelids tattooing, eyelash extensions, botulinum toxin injections for aesthetic purposes, etc.). They are carried out in proximate close to the eye and eyelids, causing multiple pathological reaction. The experience of observing patients, literature data, and the conducted study have showed that various cosmetological effects in the periorbital zone, whose popularity has increased in recent years, may cause the appearance of iatrogenic dry eye syndrome. The following most vivid clinical examples will help, encountered in our practice, to illustrate the data presented. Collecting the anamnesis, it is necessary to identify the presence of risk factors for the development of diseases of the ocular surface and CVD, to eliminate them, if possible, and to carry out adequate pathogenically based therapy.https://www.ophthalmojournal.com/opht/article/view/962ophthalmologydry eye syndromecosmetologybotulinum toxindermal fillerseye makeupeyelash extensions
spellingShingle V. N. Trubilin
E. G. Polunina
D. V. Angelova
V. V. Kurenkov
S. G. Kapkova
K. V. Chinenova
M. E. Konovalov
M. D. Pozharitsky
Current Concepts about the Etiology of Dry Eye Syndrome
Oftalʹmologiâ
ophthalmology
dry eye syndrome
cosmetology
botulinum toxin
dermal fillers
eye makeup
eyelash extensions
title Current Concepts about the Etiology of Dry Eye Syndrome
title_full Current Concepts about the Etiology of Dry Eye Syndrome
title_fullStr Current Concepts about the Etiology of Dry Eye Syndrome
title_full_unstemmed Current Concepts about the Etiology of Dry Eye Syndrome
title_short Current Concepts about the Etiology of Dry Eye Syndrome
title_sort current concepts about the etiology of dry eye syndrome
topic ophthalmology
dry eye syndrome
cosmetology
botulinum toxin
dermal fillers
eye makeup
eyelash extensions
url https://www.ophthalmojournal.com/opht/article/view/962
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