Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.

<h4>Objective</h4>To investigate: 1) the demographics and clinical characteristics, 2) the findings, and 3) the safety and effectiveness in a cohort of Chinese pediatric patients undergoing colonoscopy.<h4>Methods</h4>The study participants were consecutive patients aged ≤14...

Full description

Saved in:
Bibliographic Details
Main Authors: Pingguang Lei, Fang Gu, Liru Hong, Yuli Sun, Minrui Li, Huiling Wang, Bihui Zhong, Minhu Chen, Yi Cui, Shenghong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095933&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850191693565919232
author Pingguang Lei
Fang Gu
Liru Hong
Yuli Sun
Minrui Li
Huiling Wang
Bihui Zhong
Minhu Chen
Yi Cui
Shenghong Zhang
author_facet Pingguang Lei
Fang Gu
Liru Hong
Yuli Sun
Minrui Li
Huiling Wang
Bihui Zhong
Minhu Chen
Yi Cui
Shenghong Zhang
author_sort Pingguang Lei
collection DOAJ
description <h4>Objective</h4>To investigate: 1) the demographics and clinical characteristics, 2) the findings, and 3) the safety and effectiveness in a cohort of Chinese pediatric patients undergoing colonoscopy.<h4>Methods</h4>The study participants were consecutive patients aged ≤14 years old that underwent their first colonoscopy in the endoscopy center at the First Affiliated Hospital, Sun Yat-sen University between Jan. 1, 2001 and Dec. 31, 2012. Demographic, clinical, endoscopic, and pathological findings were collected.<h4>Results</h4>The cohort consisted of 322 patients, including 218 boys (67.7%) and 104 girls (32.3%). The median age was 8.0 years old and ranged from 9 months to 14 years old. Hematochezia (48.8%) and abdominal pain/discomfort (41.3%) were the most common presentations preceding pediatric colonoscopy. The caecal intubation success rate was 96.3%. No serious complications occurred during the procedures. A total of 227 patients (70.5%) received a positive diagnosis under endoscopy, including 138 patients with polyps and 53 patients with inflammatory bowel disease (IBD). Among the patients with polyps, 71.0% were juvenile polyps. Comparisons between years 2001-2006 and 2007-2012 showed that the IBD detection rate increased significantly (4.6% vs. 22.4%, P<0.001), while the opposite occurred for the polyp detection rate (73.1% vs. 27.6%, P<0.001).<h4>Conclusion</h4>Colonoscopy in pediatric patients is a safe and effective procedure. Polyps are the primary finding during colonoscopy. In South China there has been an increase in pediatric patients diagnosed with IBD over the past decade. However, a large epidemiological study is needed to confirm our findings.
format Article
id doaj-art-6cd13278e10c4fcdb143db1a623b18a3
institution OA Journals
issn 1932-6203
language English
publishDate 2014-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-6cd13278e10c4fcdb143db1a623b18a32025-08-20T02:14:50ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9593310.1371/journal.pone.0095933Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.Pingguang LeiFang GuLiru HongYuli SunMinrui LiHuiling WangBihui ZhongMinhu ChenYi CuiShenghong Zhang<h4>Objective</h4>To investigate: 1) the demographics and clinical characteristics, 2) the findings, and 3) the safety and effectiveness in a cohort of Chinese pediatric patients undergoing colonoscopy.<h4>Methods</h4>The study participants were consecutive patients aged ≤14 years old that underwent their first colonoscopy in the endoscopy center at the First Affiliated Hospital, Sun Yat-sen University between Jan. 1, 2001 and Dec. 31, 2012. Demographic, clinical, endoscopic, and pathological findings were collected.<h4>Results</h4>The cohort consisted of 322 patients, including 218 boys (67.7%) and 104 girls (32.3%). The median age was 8.0 years old and ranged from 9 months to 14 years old. Hematochezia (48.8%) and abdominal pain/discomfort (41.3%) were the most common presentations preceding pediatric colonoscopy. The caecal intubation success rate was 96.3%. No serious complications occurred during the procedures. A total of 227 patients (70.5%) received a positive diagnosis under endoscopy, including 138 patients with polyps and 53 patients with inflammatory bowel disease (IBD). Among the patients with polyps, 71.0% were juvenile polyps. Comparisons between years 2001-2006 and 2007-2012 showed that the IBD detection rate increased significantly (4.6% vs. 22.4%, P<0.001), while the opposite occurred for the polyp detection rate (73.1% vs. 27.6%, P<0.001).<h4>Conclusion</h4>Colonoscopy in pediatric patients is a safe and effective procedure. Polyps are the primary finding during colonoscopy. In South China there has been an increase in pediatric patients diagnosed with IBD over the past decade. However, a large epidemiological study is needed to confirm our findings.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095933&type=printable
spellingShingle Pingguang Lei
Fang Gu
Liru Hong
Yuli Sun
Minrui Li
Huiling Wang
Bihui Zhong
Minhu Chen
Yi Cui
Shenghong Zhang
Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
PLoS ONE
title Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
title_full Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
title_fullStr Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
title_full_unstemmed Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
title_short Pediatric colonoscopy in South China: a 12-year experience in a tertiary center.
title_sort pediatric colonoscopy in south china a 12 year experience in a tertiary center
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0095933&type=printable
work_keys_str_mv AT pingguanglei pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT fanggu pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT liruhong pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT yulisun pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT minruili pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT huilingwang pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT bihuizhong pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT minhuchen pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT yicui pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter
AT shenghongzhang pediatriccolonoscopyinsouthchinaa12yearexperienceinatertiarycenter