Corneal Cell Matrix‐Conditioned Amniotic Membrane with Improved Biochemical Properties and Corneal Wound Healing Potential: An In Vitro and In Vivo Study

Corneal Cell Matrix‐Conditioned Amniotic Membrane with Improved Biochemical Properties and Corneal Wound Healing Potential: An In Vitro and In Vivo Study

Abstract Several attempts have been made to engineer the amniotic membrane (AM) to improve its biomechanical and biological characteristics close to corneal tissue for corneal wound dressing applications. In this study, a decellularized AM (dAM) is conditioned with limbal epithelial stem cells (LESC...

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Main Authors: Zeinab Nokhbedehghan, Zahra Esmaeili, Seyed‐Hashem Daryabari, Hossein Aghamollaei, Sara Simorgh, Jila Majidi, Sanaz Alizadeh, Sadjad Khosravimelal, Narendra Pal Singh Chauhan, Hajar Nasiri, Mazaher Gholipourmalekabadi
Format: Article
Language:English
Published: Wiley-VCH 2025-06-01
Series:Macromolecular Materials and Engineering
Subjects:
amniotic membrane
corneal tissue engineering
corneal wound dressing
extracellular matrix
stem cells conditioning
Online Access:https://doi.org/10.1002/mame.202400390
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