Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman
Background. To report a case of a pregnant woman with sickle cell trait (SCT) who presented with unilateral proliferative sickle cell retinopathy. Case Presentation. A 26-year-old otherwise healthy pregnant woman presented with the complaint of visual loss in her left eye. The funduscopic examinatio...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/5988889 |
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| author | Sepideh Ghods Elias Khalili Pour Hooshang Faghihi Golnaz Gharehbaghi Ahmad Mirshahi Fariba Ghassemi Bahman Inanloo Hamid Riazi-Esfahani |
| author_facet | Sepideh Ghods Elias Khalili Pour Hooshang Faghihi Golnaz Gharehbaghi Ahmad Mirshahi Fariba Ghassemi Bahman Inanloo Hamid Riazi-Esfahani |
| author_sort | Sepideh Ghods |
| collection | DOAJ |
| description | Background. To report a case of a pregnant woman with sickle cell trait (SCT) who presented with unilateral proliferative sickle cell retinopathy. Case Presentation. A 26-year-old otherwise healthy pregnant woman presented with the complaint of visual loss in her left eye. The funduscopic examination showed vitreous hemorrhage, sea fan neovascularization, and pale optic disc. Optical coherence tomography revealed macular inner retinal layer thinning and foveal splaying (saucerization of the foveal pit). The investigations, including hemoglobin electrophoresis, verified the diagnosis of sickle cell trait. Blood pressure, fasting blood glucose tests, and tuberculin skin tests were normal. We treated the patient by peripheral retinal photocoagulation over the area of nonperfusion. Conclusion. Even though the sickle cell trait is generally considered as a milder form of sickle cell disease without severe retinal manifestations, pregnancy should be considered as a trigger that can induce proliferative changes and foveal splaying in this group of patients. |
| format | Article |
| id | doaj-art-6ccc2181b17c4fc4a82b20843356f51d |
| institution | Kabale University |
| issn | 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-6ccc2181b17c4fc4a82b20843356f51d2025-02-03T01:26:56ZengWileyCase Reports in Ophthalmological Medicine2090-67302021-01-01202110.1155/2021/5988889Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant WomanSepideh Ghods0Elias Khalili Pour1Hooshang Faghihi2Golnaz Gharehbaghi3Ahmad Mirshahi4Fariba Ghassemi5Bahman Inanloo6Hamid Riazi-Esfahani7Eye Research CenterEye Research CenterEye Research CenterAliasghar Clinical Research Development CenterEye Research CenterEye Research CenterEye Research CenterEye Research CenterBackground. To report a case of a pregnant woman with sickle cell trait (SCT) who presented with unilateral proliferative sickle cell retinopathy. Case Presentation. A 26-year-old otherwise healthy pregnant woman presented with the complaint of visual loss in her left eye. The funduscopic examination showed vitreous hemorrhage, sea fan neovascularization, and pale optic disc. Optical coherence tomography revealed macular inner retinal layer thinning and foveal splaying (saucerization of the foveal pit). The investigations, including hemoglobin electrophoresis, verified the diagnosis of sickle cell trait. Blood pressure, fasting blood glucose tests, and tuberculin skin tests were normal. We treated the patient by peripheral retinal photocoagulation over the area of nonperfusion. Conclusion. Even though the sickle cell trait is generally considered as a milder form of sickle cell disease without severe retinal manifestations, pregnancy should be considered as a trigger that can induce proliferative changes and foveal splaying in this group of patients.http://dx.doi.org/10.1155/2021/5988889 |
| spellingShingle | Sepideh Ghods Elias Khalili Pour Hooshang Faghihi Golnaz Gharehbaghi Ahmad Mirshahi Fariba Ghassemi Bahman Inanloo Hamid Riazi-Esfahani Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman Case Reports in Ophthalmological Medicine |
| title | Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman |
| title_full | Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman |
| title_fullStr | Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman |
| title_full_unstemmed | Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman |
| title_short | Sickle Cell Trait Presenting as Unilateral Proliferative Retinopathy and Macular Thinning in a Pregnant Woman |
| title_sort | sickle cell trait presenting as unilateral proliferative retinopathy and macular thinning in a pregnant woman |
| url | http://dx.doi.org/10.1155/2021/5988889 |
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