Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states
GERD and iodine deficiency conditions are not only limited by similar clinical symptoms. They influence on each other by regulatory kinetic mechanisms of upper gastrointestinal tract. Aim. We examined 40 patients with GERD on a background of iodine deficiency in order to study the efficacy of us...
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| Format: | Article |
| Language: | English |
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Zaporizhzhia State Medical and Pharmaceutical University
2015-04-01
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| Series: | Zaporožskij Medicinskij Žurnal |
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| Online Access: | http://zmj.zsmu.edu.ua/article/view/42051/38341 |
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| author | V. B. Boychuk |
| author_facet | V. B. Boychuk |
| author_sort | V. B. Boychuk |
| collection | DOAJ |
| description | GERD and iodine deficiency conditions are not only limited by similar clinical symptoms. They influence on each other by regulatory kinetic mechanisms of upper gastrointestinal tract.
Aim. We examined 40 patients with GERD on a background of iodine deficiency in order to study the efficacy of using potassium iodide in these patients.
Methods and results. Iodine deficiency was detected by level of iodine in urine, level of TSH, free T4 and free T3. Also was determined motor-evacuational function of the stomach according to 13C-octanoic breath test and levels of regulatory peptides (gastrin, cholecystokinin-pankreozymin and pepsinogens).
Conclusion. Positive dynamics of iodine absorption and motor-evacuational function of the stomach were found after 1 month of treatment. Decreasing frequency and duration of acid reflux and reducing pepsinogen levels and improvement of indicators of intestinal hormones were also found in these patiens. This shows the optimization of regulatory mechanisms and kinetics of upper gastrointestinal tract. |
| format | Article |
| id | doaj-art-6cbbf82fcb224099becb6e42e1d737eb |
| institution | Kabale University |
| issn | 2306-4145 2310-1210 |
| language | English |
| publishDate | 2015-04-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj-art-6cbbf82fcb224099becb6e42e1d737eb2025-08-20T03:34:09ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102015-04-0125762http://dx.doi.org/10.14739/2310-1210.2015.2.42051Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency statesV. B. BoychukGERD and iodine deficiency conditions are not only limited by similar clinical symptoms. They influence on each other by regulatory kinetic mechanisms of upper gastrointestinal tract. Aim. We examined 40 patients with GERD on a background of iodine deficiency in order to study the efficacy of using potassium iodide in these patients. Methods and results. Iodine deficiency was detected by level of iodine in urine, level of TSH, free T4 and free T3. Also was determined motor-evacuational function of the stomach according to 13C-octanoic breath test and levels of regulatory peptides (gastrin, cholecystokinin-pankreozymin and pepsinogens). Conclusion. Positive dynamics of iodine absorption and motor-evacuational function of the stomach were found after 1 month of treatment. Decreasing frequency and duration of acid reflux and reducing pepsinogen levels and improvement of indicators of intestinal hormones were also found in these patiens. This shows the optimization of regulatory mechanisms and kinetics of upper gastrointestinal tract.http://zmj.zsmu.edu.ua/article/view/42051/38341Gastroesophageal Reflux DiseaseIodineEndemic GoiterHormones |
| spellingShingle | V. B. Boychuk Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states Zaporožskij Medicinskij Žurnal Gastroesophageal Reflux Disease Iodine Endemic Goiter Hormones |
| title | Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states |
| title_full | Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states |
| title_fullStr | Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states |
| title_full_unstemmed | Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states |
| title_short | Effectiveness of potassium iodide in the treatment of GERD patients in combination with iodine deficiency states |
| title_sort | effectiveness of potassium iodide in the treatment of gerd patients in combination with iodine deficiency states |
| topic | Gastroesophageal Reflux Disease Iodine Endemic Goiter Hormones |
| url | http://zmj.zsmu.edu.ua/article/view/42051/38341 |
| work_keys_str_mv | AT vbboychuk effectivenessofpotassiumiodideinthetreatmentofgerdpatientsincombinationwithiodinedeficiencystates |