Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective
Background and objectiveThe coronavirus disease 2019 (COVID-19) pandemic marks the biggest public health emergency of the 21st century. The long-term health issues linked to COVID-19, also known as Long COVID, pose a great challenge to patients and society. This article aims to highlight the current...
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1453167/full |
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| author | Majid AlShamrani Fayssal Farahat Abdullah Assiri Sami AlHajjar Ali Albarrak Hashem AlHashemi Mohammed AlZunitan Meshal AlAqeel Sami AlYami Ziad A. Memish Ziad A. Memish Ziad A. Memish |
| author_facet | Majid AlShamrani Fayssal Farahat Abdullah Assiri Sami AlHajjar Ali Albarrak Hashem AlHashemi Mohammed AlZunitan Meshal AlAqeel Sami AlYami Ziad A. Memish Ziad A. Memish Ziad A. Memish |
| author_sort | Majid AlShamrani |
| collection | DOAJ |
| description | Background and objectiveThe coronavirus disease 2019 (COVID-19) pandemic marks the biggest public health emergency of the 21st century. The long-term health issues linked to COVID-19, also known as Long COVID, pose a great challenge to patients and society. This article aims to highlight the current unmet clinical needs and present expert recommendations for region-specific assessment and management of Long COVID.MethodsA secondary desk research was performed focusing on global and regional guidelines for the assessment and management of Long COVID. The observations from the desk research form the foundation for the consensus statements. Additionally, an expert panel consisting of 10 consultant physicians from related specialties reviewed these guidelines and literature in advisory board meetings to identify unmet needs, bridge clinical gaps, and develop recommendations for the evaluation and management of Long COVID.ResultsThe expert recommendation statements were drafted based on overarching principles for the clinical assessment and management of Long COVID. The overarching principles used a targeted, multidisciplinary approach, and collaboration between multiple specialties of healthcare. The panel also highlighted the value of holistic care for the management of Long COVID.ConclusionLong COVID is a major public health challenge. These expert recommendations are expected to guide healthcare professionals in their clinical decision-making for the assessment, management, and appropriate rehabilitation of patients with Long COVID. |
| format | Article |
| id | doaj-art-6cbb9ea03d854e1094aaaaccb912861a |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-6cbb9ea03d854e1094aaaaccb912861a2025-08-20T03:44:35ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-08-011210.3389/fmed.2025.14531671453167Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspectiveMajid AlShamrani0Fayssal Farahat1Abdullah Assiri2Sami AlHajjar3Ali Albarrak4Hashem AlHashemi5Mohammed AlZunitan6Meshal AlAqeel7Sami AlYami8Ziad A. Memish9Ziad A. Memish10Ziad A. Memish11Infection Prevention and Control Program, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi ArabiaInfection Prevention and Control Program, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi ArabiaMinistry of Health, Riyadh, Saudi ArabiaPediatric Infectious Diseases, Department of Pediatrics, King Faisal Specialist Hospital and Research Center, College of Medicine, AlFaisal University, Riyadh, Saudi ArabiaDepartment of Internal Medicine and Infectious Diseases, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaDepartment of Rehabilitation Medicine, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Jeddah, Saudi ArabiaInfection Prevention and Control Program, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi ArabiaSection of Psychiatry, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi ArabiaDepartment of Respiratory Medicine, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi ArabiaKing Salman Humanitarian Aid & Relief Center (KSrelief) and College of Medicine, Alfaisal University, Riyadh, Saudi ArabiaHubert Department of Global Health, Emory University, Atlanta, GA, United States0Abu Dhabi University, Abu Dhabi, Saudi ArabiaBackground and objectiveThe coronavirus disease 2019 (COVID-19) pandemic marks the biggest public health emergency of the 21st century. The long-term health issues linked to COVID-19, also known as Long COVID, pose a great challenge to patients and society. This article aims to highlight the current unmet clinical needs and present expert recommendations for region-specific assessment and management of Long COVID.MethodsA secondary desk research was performed focusing on global and regional guidelines for the assessment and management of Long COVID. The observations from the desk research form the foundation for the consensus statements. Additionally, an expert panel consisting of 10 consultant physicians from related specialties reviewed these guidelines and literature in advisory board meetings to identify unmet needs, bridge clinical gaps, and develop recommendations for the evaluation and management of Long COVID.ResultsThe expert recommendation statements were drafted based on overarching principles for the clinical assessment and management of Long COVID. The overarching principles used a targeted, multidisciplinary approach, and collaboration between multiple specialties of healthcare. The panel also highlighted the value of holistic care for the management of Long COVID.ConclusionLong COVID is a major public health challenge. These expert recommendations are expected to guide healthcare professionals in their clinical decision-making for the assessment, management, and appropriate rehabilitation of patients with Long COVID.https://www.frontiersin.org/articles/10.3389/fmed.2025.1453167/fullLong COVIDpost-acute sequelae of COVID-19 (PASC)post COVID-19 condition (PCC)recommendationsmanagement |
| spellingShingle | Majid AlShamrani Fayssal Farahat Abdullah Assiri Sami AlHajjar Ali Albarrak Hashem AlHashemi Mohammed AlZunitan Meshal AlAqeel Sami AlYami Ziad A. Memish Ziad A. Memish Ziad A. Memish Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective Frontiers in Medicine Long COVID post-acute sequelae of COVID-19 (PASC) post COVID-19 condition (PCC) recommendations management |
| title | Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective |
| title_full | Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective |
| title_fullStr | Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective |
| title_full_unstemmed | Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective |
| title_short | Consensus based recommendations for the management of post-COVID long-term sequelae (Long COVID): a regional perspective |
| title_sort | consensus based recommendations for the management of post covid long term sequelae long covid a regional perspective |
| topic | Long COVID post-acute sequelae of COVID-19 (PASC) post COVID-19 condition (PCC) recommendations management |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1453167/full |
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