A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective
Abstract Burn injuries are a significant cause of morbidity and mortality in pediatric populations. Our study aims to provide an in-depth overview of the current emergency treatment strategies for dermal injuries in children. While advances in burn care have led to improved outcomes for patients wit...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | Italian Journal of Pediatrics |
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| Online Access: | https://doi.org/10.1186/s13052-025-02066-9 |
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| author | Luigi Coppola Alessandra Cianflone Pasquale Primo Alessandra Macrì Fiorenza Mastrodonato Angela Iannicelli Rosanna Parasole Francesca Zamparelli Marcello Zamparelli Peppino Mirabelli |
| author_facet | Luigi Coppola Alessandra Cianflone Pasquale Primo Alessandra Macrì Fiorenza Mastrodonato Angela Iannicelli Rosanna Parasole Francesca Zamparelli Marcello Zamparelli Peppino Mirabelli |
| author_sort | Luigi Coppola |
| collection | DOAJ |
| description | Abstract Burn injuries are a significant cause of morbidity and mortality in pediatric populations. Our study aims to provide an in-depth overview of the current emergency treatment strategies for dermal injuries in children. While advances in burn care have led to improved outcomes for patients with dermal injuries, there remains considerable variability in treatment approaches, and numerous opportunities exist to enhance patient care through the adoption of novel therapies and more effective management of healthcare resources. Children with severe burns often experience profound physiological changes that can result in a range of complications, including infections, fluid and metabolism imbalance due to increased catabolism and protein requirements. Our systematic review focuses on emergency treatment approaches that have demonstrated direct application in pediatric burn care. To this aim, we consulted the scientific databases PubMed, Embase, Web of Science, and Cochrane Library, selecting n = 6 studies that outline the emergency therapeutic approach used in the pediatric setting after a burn, highlighting the most widely adopted techniques and their clinical applications. Study selection was guided by defined eligibility criteria; only original articles published in English that investigated emergency interventions in pediatric populations (0 to 17 years) were considered. Studies were excluded if they involved subjects over 17 years of age, focused on conditions unrelated to burns, employed in vitro or in vivo models, or were review articles. Through a comprehensive examination of these approaches, our study aims to identify areas for improvement and potential advancements in pediatric burn management, suggesting possible future approaches based on Advanced therapy medicinal products (ATMPs) storage approaches. |
| format | Article |
| id | doaj-art-6cb51c6aaa954ddfb41cf7f26a83c44b |
| institution | Kabale University |
| issn | 1824-7288 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Italian Journal of Pediatrics |
| spelling | doaj-art-6cb51c6aaa954ddfb41cf7f26a83c44b2025-08-20T03:43:25ZengBMCItalian Journal of Pediatrics1824-72882025-07-015111810.1186/s13052-025-02066-9A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspectiveLuigi Coppola0Alessandra Cianflone1Pasquale Primo2Alessandra Macrì3Fiorenza Mastrodonato4Angela Iannicelli5Rosanna Parasole6Francesca Zamparelli7Marcello Zamparelli8Peppino Mirabelli9UOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNUOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNUOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNUOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNUOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNUOC Clinical and Translational Research, Santobono-Pausilipon Children’s Hospital, AORNUOC Clinical and Translational Research, Santobono-Pausilipon Children’s Hospital, AORNUOSD Plastic Surgery and Pediatric Burns Center, Santobono Pausilipon National Children’s HospitalUOSD Plastic Surgery and Pediatric Burns Center, Santobono Pausilipon National Children’s HospitalUOS Laboratori di Ricerca e Biobanca, Santobono-Pausilipon Children’s Hospital, AORNAbstract Burn injuries are a significant cause of morbidity and mortality in pediatric populations. Our study aims to provide an in-depth overview of the current emergency treatment strategies for dermal injuries in children. While advances in burn care have led to improved outcomes for patients with dermal injuries, there remains considerable variability in treatment approaches, and numerous opportunities exist to enhance patient care through the adoption of novel therapies and more effective management of healthcare resources. Children with severe burns often experience profound physiological changes that can result in a range of complications, including infections, fluid and metabolism imbalance due to increased catabolism and protein requirements. Our systematic review focuses on emergency treatment approaches that have demonstrated direct application in pediatric burn care. To this aim, we consulted the scientific databases PubMed, Embase, Web of Science, and Cochrane Library, selecting n = 6 studies that outline the emergency therapeutic approach used in the pediatric setting after a burn, highlighting the most widely adopted techniques and their clinical applications. Study selection was guided by defined eligibility criteria; only original articles published in English that investigated emergency interventions in pediatric populations (0 to 17 years) were considered. Studies were excluded if they involved subjects over 17 years of age, focused on conditions unrelated to burns, employed in vitro or in vivo models, or were review articles. Through a comprehensive examination of these approaches, our study aims to identify areas for improvement and potential advancements in pediatric burn management, suggesting possible future approaches based on Advanced therapy medicinal products (ATMPs) storage approaches.https://doi.org/10.1186/s13052-025-02066-9Burns injuryEmergencyPediatricsATMPs |
| spellingShingle | Luigi Coppola Alessandra Cianflone Pasquale Primo Alessandra Macrì Fiorenza Mastrodonato Angela Iannicelli Rosanna Parasole Francesca Zamparelli Marcello Zamparelli Peppino Mirabelli A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective Italian Journal of Pediatrics Burns injury Emergency Pediatrics ATMPs |
| title | A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective |
| title_full | A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective |
| title_fullStr | A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective |
| title_full_unstemmed | A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective |
| title_short | A systematic study of emergency strategies for skin healing after pediatric burns: a comprehensive review and a multidisciplinary perspective |
| title_sort | systematic study of emergency strategies for skin healing after pediatric burns a comprehensive review and a multidisciplinary perspective |
| topic | Burns injury Emergency Pediatrics ATMPs |
| url | https://doi.org/10.1186/s13052-025-02066-9 |
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