B‐cell depletion limits HTLV‐1‐infected T‐cell expansion and ameliorate HTLV‐1‐associated myelopathy

B‐cell depletion limits HTLV‐1‐infected T‐cell expansion and ameliorate HTLV‐1‐associated myelopathy

Abstract Objective Human T‐cell leukemia virus type 1‐associated myelopathy (HAM) is a chronic, progressive, inflammatory disease with unclear pathogenesis and no effective treatments. We aimed to investigate a novel mechanistic theory and treat HAM patients with rituximab, which can deplete CD20+ B...

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Main Authors: Aowei Lv, Yaofeng Fang, Xiaohong Lin, Jiaying Chen, Huanhuan Song, Ning Wang, Wan‐Jin Chen, Ying Fu, Rui Li, Yi Lin
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.52190
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