Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona

Cavitary pneumonia, characterized by gas-filled spaces within lung tissue, is commonly associated with bacterial pathogens, such as Staphylococcus aureus, Streptococcus, Pseudomonas, and Klebsiella species. This study aimed to investigate the most common causes of cavitary pneumonia in southern Ariz...

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Main Authors: Rawan El Kurdi, Krish H. Nayar, Michael B. Gotway, Janis Blair, Sandhya Nagarakanti
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:American Journal of Medicine Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2667036425000044
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author Rawan El Kurdi
Krish H. Nayar
Michael B. Gotway
Janis Blair
Sandhya Nagarakanti
author_facet Rawan El Kurdi
Krish H. Nayar
Michael B. Gotway
Janis Blair
Sandhya Nagarakanti
author_sort Rawan El Kurdi
collection DOAJ
description Cavitary pneumonia, characterized by gas-filled spaces within lung tissue, is commonly associated with bacterial pathogens, such as Staphylococcus aureus, Streptococcus, Pseudomonas, and Klebsiella species. This study aimed to investigate the most common causes of cavitary pneumonia in southern Arizona, where coccidioidomycosis is endemic. Fungal infections were the predominant cause of cavitary pneumonia (69%), either alone or in association with bacterial infections. Seven percent of patients had concurrent fungal and bacterial infections. Overall, coccidioidomycosis was the most common cause of cavitary pneumonia, accounting for 39% of all cases and 82% of fungal cases. Among these, 24% had proven coccidioidomycosis, 51% had probable infections, and 25% had possible infections. Bacterial infections accounted for 30% of cavitary pneumonia cases, with Staphylococcus aureus (12%), Streptococcus species (12%), and Pseudomonas species (11%) being the most prevalent organisms. Overall mortality was 25%, with 34% of deaths directly attributed to cavitary pneumonia.
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issn 2667-0364
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publishDate 2025-06-01
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series American Journal of Medicine Open
spelling doaj-art-6caab01700bc4a94be0bd48f2df8200e2025-08-20T02:05:10ZengElsevierAmerican Journal of Medicine Open2667-03642025-06-011310009010.1016/j.ajmo.2025.100090Cavitary Pneumonia Causes in the Arid Landscapes of Southern ArizonaRawan El Kurdi0Krish H. Nayar1Michael B. Gotway2Janis Blair3Sandhya Nagarakanti4Department of Internal Medicine, University of Arizona, Phoenix, AZCandidate, Mayo Clinic Alix School of Medicine, Phoenix, AZDepartment of Radiology, Mayo Clinic Arizona, Phoenix, AZDivision of Infectious Diseases, Mayo Clinic, Phoenix, AZDivision of Infectious Diseases, Mayo Clinic, Phoenix, AZ; Correspondence to: Sandhya Nagarakanti, MD, Mayo Clinic Arizona, Division of Infectious Diseases, 5777 East Mayo Blvd., Phoenix, AZ, 85054;Cavitary pneumonia, characterized by gas-filled spaces within lung tissue, is commonly associated with bacterial pathogens, such as Staphylococcus aureus, Streptococcus, Pseudomonas, and Klebsiella species. This study aimed to investigate the most common causes of cavitary pneumonia in southern Arizona, where coccidioidomycosis is endemic. Fungal infections were the predominant cause of cavitary pneumonia (69%), either alone or in association with bacterial infections. Seven percent of patients had concurrent fungal and bacterial infections. Overall, coccidioidomycosis was the most common cause of cavitary pneumonia, accounting for 39% of all cases and 82% of fungal cases. Among these, 24% had proven coccidioidomycosis, 51% had probable infections, and 25% had possible infections. Bacterial infections accounted for 30% of cavitary pneumonia cases, with Staphylococcus aureus (12%), Streptococcus species (12%), and Pseudomonas species (11%) being the most prevalent organisms. Overall mortality was 25%, with 34% of deaths directly attributed to cavitary pneumonia.http://www.sciencedirect.com/science/article/pii/S2667036425000044
spellingShingle Rawan El Kurdi
Krish H. Nayar
Michael B. Gotway
Janis Blair
Sandhya Nagarakanti
Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
American Journal of Medicine Open
title Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
title_full Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
title_fullStr Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
title_full_unstemmed Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
title_short Cavitary Pneumonia Causes in the Arid Landscapes of Southern Arizona
title_sort cavitary pneumonia causes in the arid landscapes of southern arizona
url http://www.sciencedirect.com/science/article/pii/S2667036425000044
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