Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats

The aim of the present study is a comparative assessment of the echocardiographic characteristics in female and male mongrel rats. In experiments on anesthetized rats (ketamine 100 mg / kg, iv), it was shown that in female rats, the size and volume of the left ventricle are smaller than in males, bu...

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Main Authors: E. O. Ionova, E. I. Barchukova, M. B. Vititnova, I. B. Tsorin, S. A. Kryzhanovskii
Format: Article
Language:Russian
Published: LLC “Publisher OKI” 2021-09-01
Series:Фармакокинетика и Фармакодинамика
Subjects:
Online Access:https://www.pharmacokinetica.ru/jour/article/view/267
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author E. O. Ionova
E. I. Barchukova
M. B. Vititnova
I. B. Tsorin
S. A. Kryzhanovskii
author_facet E. O. Ionova
E. I. Barchukova
M. B. Vititnova
I. B. Tsorin
S. A. Kryzhanovskii
author_sort E. O. Ionova
collection DOAJ
description The aim of the present study is a comparative assessment of the echocardiographic characteristics in female and male mongrel rats. In experiments on anesthetized rats (ketamine 100 mg / kg, iv), it was shown that in female rats, the size and volume of the left ventricle are smaller than in males, but compared with males, their left ventricular ejection fraction, which characterizes its inotropic function, is statistically significantly higher.
format Article
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institution DOAJ
issn 2587-7836
2686-8830
language Russian
publishDate 2021-09-01
publisher LLC “Publisher OKI”
record_format Article
series Фармакокинетика и Фармакодинамика
spelling doaj-art-6ca0f6689cf8459cbb8c49d69737d30f2025-08-20T03:19:57ZrusLLC “Publisher OKI”Фармакокинетика и Фармакодинамика2587-78362686-88302021-09-0101141710.37489/2587-7836-2021-1-14-17262Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male ratsE. O. Ionova0E. I. Barchukova1M. B. Vititnova2I. B. Tsorin3S. A. Kryzhanovskii4FSBI “Zakusov Institute of Pharmacology”FSBI “Zakusov Institute of Pharmacology”FSBI “Zakusov Institute of Pharmacology”FSBI “Zakusov Institute of Pharmacology”FSBI “Zakusov Institute of Pharmacology”The aim of the present study is a comparative assessment of the echocardiographic characteristics in female and male mongrel rats. In experiments on anesthetized rats (ketamine 100 mg / kg, iv), it was shown that in female rats, the size and volume of the left ventricle are smaller than in males, but compared with males, their left ventricular ejection fraction, which characterizes its inotropic function, is statistically significantly higher.https://www.pharmacokinetica.ru/jour/article/view/267echocardiographyratsmalesfemalessex differences
spellingShingle E. O. Ionova
E. I. Barchukova
M. B. Vititnova
I. B. Tsorin
S. A. Kryzhanovskii
Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
Фармакокинетика и Фармакодинамика
echocardiography
rats
males
females
sex differences
title Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
title_full Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
title_fullStr Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
title_full_unstemmed Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
title_short Comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
title_sort comparative evaluation of echocardiographic characteristics of the heart left ventricle in female and male rats
topic echocardiography
rats
males
females
sex differences
url https://www.pharmacokinetica.ru/jour/article/view/267
work_keys_str_mv AT eoionova comparativeevaluationofechocardiographiccharacteristicsoftheheartleftventricleinfemaleandmalerats
AT eibarchukova comparativeevaluationofechocardiographiccharacteristicsoftheheartleftventricleinfemaleandmalerats
AT mbvititnova comparativeevaluationofechocardiographiccharacteristicsoftheheartleftventricleinfemaleandmalerats
AT ibtsorin comparativeevaluationofechocardiographiccharacteristicsoftheheartleftventricleinfemaleandmalerats
AT sakryzhanovskii comparativeevaluationofechocardiographiccharacteristicsoftheheartleftventricleinfemaleandmalerats