Anemia in Children with Down Syndrome
Background. Iron deficiency anemia impacts on cognitive development. The objective of this study was to determine the prevalence of anemia and iron deficiency in children with Down syndrome and identify risk factors for anemia. Methods. We conducted a prolective cross-sectional study of children att...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2011/813541 |
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| author | Ariel Tenenbaum Sarah Malkiel Isaiah D. Wexler Floris Levy-Khademi Shoshana Revel-Vilk Polina Stepensky |
| author_facet | Ariel Tenenbaum Sarah Malkiel Isaiah D. Wexler Floris Levy-Khademi Shoshana Revel-Vilk Polina Stepensky |
| author_sort | Ariel Tenenbaum |
| collection | DOAJ |
| description | Background. Iron deficiency anemia impacts on cognitive development. The objective of this study was to determine the prevalence of anemia and iron deficiency in children with Down syndrome and identify risk factors for anemia. Methods. We conducted a prolective cross-sectional study of children attending a multidisciplinary Down syndrome medical center. One hundred and forty nine children with Down syndrome aged 0–20 years were enrolled in the study. Information obtained included a medical history, physical and developmental examination, nutritional assessment, and the results of blood tests. Results. Of the patients studied, 8.1% were found to have anemia. Among the 38 children who had iron studies, 50.0% had iron deficiency. In a multivariate analysis, Arab ethnicity and low weight for age were significantly associated with anemia. Gender, height, the presence of an eating disorder, and congenital heart disease were not risk factors for anemia. Conclusions. Children with Down syndrome are at risk for anemia and iron deficiency similar to the general population. Children with Down syndrome should be monitored for anemia and iron deficiency so that prompt intervention can be initiated. |
| format | Article |
| id | doaj-art-6c9db387f44145d0b40b17a327cbc66b |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-6c9db387f44145d0b40b17a327cbc66b2025-08-20T03:34:09ZengWileyInternational Journal of Pediatrics1687-97401687-97592011-01-01201110.1155/2011/813541813541Anemia in Children with Down SyndromeAriel Tenenbaum0Sarah Malkiel1Isaiah D. Wexler2Floris Levy-Khademi3Shoshana Revel-Vilk4Polina Stepensky5Department of Pediatrics, Hadassah University Medical Center, Mount Scopus Campus, Jerusalem, IsraelDepartment of Pediatrics, Hadassah University Medical Center, Mount Scopus Campus, Jerusalem, IsraelDepartment of Pediatrics, Hadassah University Medical Center, Mount Scopus Campus, Jerusalem, IsraelDepartment of Pediatrics, Hadassah University Medical Center, Mount Scopus Campus, Jerusalem, IsraelDepartment of Pediatric Hematology Oncology, Hadassah University Medical Center, Ein Kerem Campus, Jerusalem, IsraelDepartment of Pediatric Hematology Oncology, Hadassah University Medical Center, Ein Kerem Campus, Jerusalem, IsraelBackground. Iron deficiency anemia impacts on cognitive development. The objective of this study was to determine the prevalence of anemia and iron deficiency in children with Down syndrome and identify risk factors for anemia. Methods. We conducted a prolective cross-sectional study of children attending a multidisciplinary Down syndrome medical center. One hundred and forty nine children with Down syndrome aged 0–20 years were enrolled in the study. Information obtained included a medical history, physical and developmental examination, nutritional assessment, and the results of blood tests. Results. Of the patients studied, 8.1% were found to have anemia. Among the 38 children who had iron studies, 50.0% had iron deficiency. In a multivariate analysis, Arab ethnicity and low weight for age were significantly associated with anemia. Gender, height, the presence of an eating disorder, and congenital heart disease were not risk factors for anemia. Conclusions. Children with Down syndrome are at risk for anemia and iron deficiency similar to the general population. Children with Down syndrome should be monitored for anemia and iron deficiency so that prompt intervention can be initiated.http://dx.doi.org/10.1155/2011/813541 |
| spellingShingle | Ariel Tenenbaum Sarah Malkiel Isaiah D. Wexler Floris Levy-Khademi Shoshana Revel-Vilk Polina Stepensky Anemia in Children with Down Syndrome International Journal of Pediatrics |
| title | Anemia in Children with Down Syndrome |
| title_full | Anemia in Children with Down Syndrome |
| title_fullStr | Anemia in Children with Down Syndrome |
| title_full_unstemmed | Anemia in Children with Down Syndrome |
| title_short | Anemia in Children with Down Syndrome |
| title_sort | anemia in children with down syndrome |
| url | http://dx.doi.org/10.1155/2011/813541 |
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