Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China

Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China

BackgroundMedulloblastoma (MB) is the most common malignant pediatric brain tumor, yet systematic studies on molecular characteristics and treatment efficacy in Chinese pediatric MB remain scarce. This study evaluates recurrence and mortality risk factors and the feasibility of intensified chemother...

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Bibliographic Details
Main Authors: Jingjing Liu, Yanling Sun, Huming Li, Shuxu Du, Jin Zhang, Zhen Zhang, Liming Sun, Wanshui Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
medulloblastoma
risk factors for relapse and mortality
maintain chemotherapy by risk stratification
large cohort
real-world study
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1597123/full
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