Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

Neuroprotective Effect of Mixed Mushroom Mycelia Extract on Neurotoxicity and Neuroinflammation via Regulation of ROS-Induced Oxidative Stress in PC12 and BV2 Cells

In this study, we investigated the potential of a three-mushroom complex extract (GMK) to inhibit neuronal cell death induced by the activation of AMPA and NMDA receptors following glutamate treatment in NGF-differentiated PC12 neuronal cells. GMK significantly mitigated glutamate-induced excitotoxi...

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Bibliographic Details
Main Authors: Sang-Seop Lee, Da-Hyun Ko, Ga-Young Lee, So-Yeon Kim, Seung-Yun Han, Jong-Yea Park, MiNa Park, Hyun-Min Kim, Ya-El Kim, Yung-Choon Yoo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
mushroom mycelial extract
excitotoxicity
neuroinflammation
PC12 neurons
BV2 microglia
ROS
Online Access:https://www.mdpi.com/2073-4409/14/13/977
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