Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis
Invasive infection may complicate the course of neutropenic cancer patients receiving intensive chemotherapy. The rate of complications is related to prognostic factors including the underlying malignant diagnosis, the state of responsiveness of the underlying disease to treatment, the dose-intensit...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2000-01-01
|
| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2000/509358 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849413357330759680 |
|---|---|
| author | Coleman Rotstein Eric J Bow The Febrile Neutropenia Care Plan Working Group |
| author_facet | Coleman Rotstein Eric J Bow The Febrile Neutropenia Care Plan Working Group |
| author_sort | Coleman Rotstein |
| collection | DOAJ |
| description | Invasive infection may complicate the course of neutropenic cancer patients receiving intensive chemotherapy. The rate
of complications is related to prognostic factors including the underlying malignant diagnosis, the state of responsiveness
of the underlying disease to treatment, the dose-intensity of the cytotoxic therapy, the duration of neutropenia, the
performance status of the patient and comorbid conditions. The pathogens involved are usually the patients’ endogenous
microflora, and the sites of infection are those anatomic sites colonized with the endogenous microflora. The approach
to the febrile neutropenic episode requires a sequence of steps including the recognition of the febrile state (oral
temperature higher than 38°C), the depth and duration of the neutropenia (absolute neutrophil count less than
0.5×109/L), the identification of a clinical focus of infection and a potential pathogen, the administration of empirical antibacterial
therapy, and finally, an assessment of the outcome. Management decisions about whether to treat with oral
or parenteral antibacterial agents, with a combination or single agent therapy, or as an inpatient or an outpatient can be
based on an assessments of risks of the severity of the patient’s comorbid conditions and the patient’s risk of developing
medical complications that would require inpatient management. The duration of antimicrobial treatment depends on
the recovery from the state of neutropenia and the origin of the infectious process. |
| format | Article |
| id | doaj-art-6c8c98817e5b46239b8eacba2c4cef31 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-6c8c98817e5b46239b8eacba2c4cef312025-08-20T03:34:09ZengWileyCanadian Journal of Infectious Diseases1180-23322000-01-0111Suppl D27D33D10.1155/2000/509358Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient BasisColeman Rotstein0Eric J Bow1The Febrile Neutropenia Care Plan Working GroupMcMaster University, Division of Infectious Diseases, Henderson Site, Hamilton Health Sciences Corporation, Hamilton, Ontario, CanadaDepartments of Internal Medicine and Medical Microbiology, Sections of Infectious Diseases and Haematology/Oncology, Head, Section of Haematology/Oncology, The University of Manitoba, and Department of Medical Oncology and Haematology, CancerCare Manitoba, Winnepeg, Manitoba, CanadaInvasive infection may complicate the course of neutropenic cancer patients receiving intensive chemotherapy. The rate of complications is related to prognostic factors including the underlying malignant diagnosis, the state of responsiveness of the underlying disease to treatment, the dose-intensity of the cytotoxic therapy, the duration of neutropenia, the performance status of the patient and comorbid conditions. The pathogens involved are usually the patients’ endogenous microflora, and the sites of infection are those anatomic sites colonized with the endogenous microflora. The approach to the febrile neutropenic episode requires a sequence of steps including the recognition of the febrile state (oral temperature higher than 38°C), the depth and duration of the neutropenia (absolute neutrophil count less than 0.5×109/L), the identification of a clinical focus of infection and a potential pathogen, the administration of empirical antibacterial therapy, and finally, an assessment of the outcome. Management decisions about whether to treat with oral or parenteral antibacterial agents, with a combination or single agent therapy, or as an inpatient or an outpatient can be based on an assessments of risks of the severity of the patient’s comorbid conditions and the patient’s risk of developing medical complications that would require inpatient management. The duration of antimicrobial treatment depends on the recovery from the state of neutropenia and the origin of the infectious process.http://dx.doi.org/10.1155/2000/509358 |
| spellingShingle | Coleman Rotstein Eric J Bow The Febrile Neutropenia Care Plan Working Group Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis Canadian Journal of Infectious Diseases |
| title | Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis |
| title_full | Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis |
| title_fullStr | Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis |
| title_full_unstemmed | Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis |
| title_short | Adult Patient Care Plan: Management of the Febrile Neutropenic Cancer Patient on an Outpatient Basis |
| title_sort | adult patient care plan management of the febrile neutropenic cancer patient on an outpatient basis |
| url | http://dx.doi.org/10.1155/2000/509358 |
| work_keys_str_mv | AT colemanrotstein adultpatientcareplanmanagementofthefebrileneutropeniccancerpatientonanoutpatientbasis AT ericjbow adultpatientcareplanmanagementofthefebrileneutropeniccancerpatientonanoutpatientbasis AT thefebrileneutropeniacareplanworkinggroup adultpatientcareplanmanagementofthefebrileneutropeniccancerpatientonanoutpatientbasis |