Effusive Constrictive Pericarditis in the Era of COVID-19

Effusive-constrictive pericarditis is a rare condition in which the visceral pericardium compresses the heart, with fluid accumulation in the pericardial space leading to cardiac tamponade. We present a case of 59-year-old man with effusive-constrictive pericarditis that was refractory to standard t...

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Bibliographic Details
Main Authors: Shriya Sharma, Si Pham, Archer Martin, Jose Ruiz, Caitlyn Luce, Aarti Desai, Rohan M. Goswami
Format: Article
Language:English
Published: American College of Physicians 2024-08-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.1360
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Summary:Effusive-constrictive pericarditis is a rare condition in which the visceral pericardium compresses the heart, with fluid accumulation in the pericardial space leading to cardiac tamponade. We present a case of 59-year-old man with effusive-constrictive pericarditis that was refractory to standard therapy. The symptoms appeared after he received a Moderna COVID-19 booster, with electrocardiogram findings showing PR depression and ST-segment elevation and cardiac imaging findings revealing abnormalities including thickened pericardium, ventricular interdependence, and septal bounce. Given the patient's abnormal hemodynamics and intolerance to high-dose nonsteroidal anti-inflammatory drugs, he was prescribed rilonacept. Because of the recalcitrant nature of his disease, pericardial stripping was done to prevent worsening of heart failure.
ISSN:2767-7664