Non-Monotonic Effect of Substrate Inhibition in Conjunction with Diffusion Limitation on the Response of Amperometric Biosensors

The non-monotonic behavior of amperometric enzyme-based biosensors under uncompetitive and noncompetitive (mixed) substrate inhibition is investigated computationally using a two-compartment model consisting of an enzyme layer and an outer diffusion layer. The model is based on a system of reaction–...

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Bibliographic Details
Main Author: Romas Baronas
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/15/7/441
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