Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer

Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer

BackgroundFibroblasts can regulate tumour development by secreting various factors. For COAD survival prediction and CAFs-based treatment recommendations, it is critical to comprehend the heterogeneity of CAFs and find biomarkers.MethodsWe identified fibroblast-associated specific marker genes in co...

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Bibliographic Details
Main Authors:	Wenbing Zhang, Chi Yang, Ye Lu, Chenling Tang, Mengyu Zhao, Zhaohui Wang, Jidong Gao, Shuangjiu Hu, Zhihua Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Immunology
Subjects:	colon adenocarcinoma cancer-associated fibroblasts signature tumor immune microenvironment MAN1B1
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1532306/full
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