Resveratrol as a potential broad-spectrum compound for cancer treatment

There is a need to shift the paradigm of cancer therapeutic approach. The severe adverse side effects, drug resistance and unaffordable price plagued with chemotherapeutic drugs has spurred the development of “dirty drug”. Natural products, specifically phytochemicals, have gained much attention du...

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Main Authors: Li Kar Stella Tan, Chee Wun How, Jhi Biau Foo, Kooi Yeong Khaw, Bey Hing Goh, Yong Sze Ong
Format: Article
Language:English
Published: HH Publisher 2020-07-01
Series:Progress in Microbes and Molecular Biology
Online Access:https://journals.hh-publisher.com/index.php/pmmb/article/view/297
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author Li Kar Stella Tan
Chee Wun How
Jhi Biau Foo
Kooi Yeong Khaw
Bey Hing Goh
Yong Sze Ong
author_facet Li Kar Stella Tan
Chee Wun How
Jhi Biau Foo
Kooi Yeong Khaw
Bey Hing Goh
Yong Sze Ong
author_sort Li Kar Stella Tan
collection DOAJ
description There is a need to shift the paradigm of cancer therapeutic approach. The severe adverse side effects, drug resistance and unaffordable price plagued with chemotherapeutic drugs has spurred the development of “dirty drug”. Natural products, specifically phytochemicals, have gained much attention due to their ability to target multiple interconnected pathways. Resveratrol (RSV), the stilbenes found in red wine, is one of the phytochemicals that exhibits various pharmacological therapeutic effects including cancer. In this review, we highlighted RSV as a potential “broad-spectrum” anticancer compound, by summarising its targeting mechanisms in the pathways relevant to the cancer hallmarks.
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institution Kabale University
issn 2637-1049
language English
publishDate 2020-07-01
publisher HH Publisher
record_format Article
series Progress in Microbes and Molecular Biology
spelling doaj-art-6c78f905eb8545e3b1baf0262124bd2d2025-02-04T08:37:02ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492020-07-013110.36877/pmmb.a0000098.Resveratrol as a potential broad-spectrum compound for cancer treatmentLi Kar Stella TanChee Wun HowJhi Biau FooKooi Yeong KhawBey Hing GohYong Sze Ong There is a need to shift the paradigm of cancer therapeutic approach. The severe adverse side effects, drug resistance and unaffordable price plagued with chemotherapeutic drugs has spurred the development of “dirty drug”. Natural products, specifically phytochemicals, have gained much attention due to their ability to target multiple interconnected pathways. Resveratrol (RSV), the stilbenes found in red wine, is one of the phytochemicals that exhibits various pharmacological therapeutic effects including cancer. In this review, we highlighted RSV as a potential “broad-spectrum” anticancer compound, by summarising its targeting mechanisms in the pathways relevant to the cancer hallmarks. https://journals.hh-publisher.com/index.php/pmmb/article/view/297
spellingShingle Li Kar Stella Tan
Chee Wun How
Jhi Biau Foo
Kooi Yeong Khaw
Bey Hing Goh
Yong Sze Ong
Resveratrol as a potential broad-spectrum compound for cancer treatment
Progress in Microbes and Molecular Biology
title Resveratrol as a potential broad-spectrum compound for cancer treatment
title_full Resveratrol as a potential broad-spectrum compound for cancer treatment
title_fullStr Resveratrol as a potential broad-spectrum compound for cancer treatment
title_full_unstemmed Resveratrol as a potential broad-spectrum compound for cancer treatment
title_short Resveratrol as a potential broad-spectrum compound for cancer treatment
title_sort resveratrol as a potential broad spectrum compound for cancer treatment
url https://journals.hh-publisher.com/index.php/pmmb/article/view/297
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AT kooiyeongkhaw resveratrolasapotentialbroadspectrumcompoundforcancertreatment
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