HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR
The present study was carried out to detect histopathologic lesions in different rat organs after chronic exposure to formaldehyde vapor. Forty adult albino Wistar rats were used in this experiment. Animals were divided into two groups; Control group (n=10; 5 males and 5 fem...
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| Format: | Article |
| Language: | English |
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College of Veterinary Medicine, University of Basrah, Iraq
2014-12-01
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| Series: | Basrah Journal of Veterinary Research |
| Subjects: | |
| Online Access: | https://bjvr.uobasrah.edu.iq/article_98805_af1a326033397d78e25f3139a69635a7.pdf |
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| author | Snur Muhammad Amin Hassan Azad Kareem Saeed Nabil Abdul-Massih Salmo Ahmed Hamdi Mehdi Nali Abdulqadr Maaruf |
| author_facet | Snur Muhammad Amin Hassan Azad Kareem Saeed Nabil Abdul-Massih Salmo Ahmed Hamdi Mehdi Nali Abdulqadr Maaruf |
| author_sort | Snur Muhammad Amin Hassan |
| collection | DOAJ |
| description | The present study was carried out to detect histopathologic lesions in different
rat organs after chronic exposure to formaldehyde vapor. Forty adult albino Wistar
rats were used in this experiment. Animals were divided into two groups; Control
group (n=10; 5 males and 5 females) which were not exposed to formaldehyde at all,
while the remainders regarded as the experimental group (exposed to formaldehyde
for 21 days, n=30; 15 males and 15 females). The histopathologic examination in our
study revealed several changes in exposed group such as; chronic tracheitis, squamous
metaplasia of lining epithelium and tracheal glands with occurrence dysplasia in the
lining epithelium, interstitial pneumonia, hydropic degeneration in the hepatocytes,
epidermal hyperplasia, interstitial glomerulonephritis with atrophy of glomeruli. We
concluded that the overexposure of formaldehyde produced lesions in different organs
but their toxic effects were seen predominantly in respiratory system. |
| format | Article |
| id | doaj-art-6c6fa71887ed4bec88673b84f57a2c49 |
| institution | Kabale University |
| issn | 1813-8497 2410-8456 |
| language | English |
| publishDate | 2014-12-01 |
| publisher | College of Veterinary Medicine, University of Basrah, Iraq |
| record_format | Article |
| series | Basrah Journal of Veterinary Research |
| spelling | doaj-art-6c6fa71887ed4bec88673b84f57a2c492025-08-20T03:49:45ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562014-12-0113212714010.33762/bvetr.2014.9880598805HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPORSnur Muhammad Amin HassanAzad Kareem SaeedNabil Abdul-Massih SalmoAhmed Hamdi MehdiNali Abdulqadr MaarufThe present study was carried out to detect histopathologic lesions in different rat organs after chronic exposure to formaldehyde vapor. Forty adult albino Wistar rats were used in this experiment. Animals were divided into two groups; Control group (n=10; 5 males and 5 females) which were not exposed to formaldehyde at all, while the remainders regarded as the experimental group (exposed to formaldehyde for 21 days, n=30; 15 males and 15 females). The histopathologic examination in our study revealed several changes in exposed group such as; chronic tracheitis, squamous metaplasia of lining epithelium and tracheal glands with occurrence dysplasia in the lining epithelium, interstitial pneumonia, hydropic degeneration in the hepatocytes, epidermal hyperplasia, interstitial glomerulonephritis with atrophy of glomeruli. We concluded that the overexposure of formaldehyde produced lesions in different organs but their toxic effects were seen predominantly in respiratory system.https://bjvr.uobasrah.edu.iq/article_98805_af1a326033397d78e25f3139a69635a7.pdftracheitisformaldehydewistar rats |
| spellingShingle | Snur Muhammad Amin Hassan Azad Kareem Saeed Nabil Abdul-Massih Salmo Ahmed Hamdi Mehdi Nali Abdulqadr Maaruf HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR Basrah Journal of Veterinary Research tracheitis formaldehyde wistar rats |
| title | HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR |
| title_full | HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR |
| title_fullStr | HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR |
| title_full_unstemmed | HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR |
| title_short | HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR |
| title_sort | histopathologic changes in rat organs upon chronic exposure to formaldehyde vapor |
| topic | tracheitis formaldehyde wistar rats |
| url | https://bjvr.uobasrah.edu.iq/article_98805_af1a326033397d78e25f3139a69635a7.pdf |
| work_keys_str_mv | AT snurmuhammadaminhassan histopathologicchangesinratorgansuponchronicexposuretoformaldehydevapor AT azadkareemsaeed histopathologicchangesinratorgansuponchronicexposuretoformaldehydevapor AT nabilabdulmassihsalmo histopathologicchangesinratorgansuponchronicexposuretoformaldehydevapor AT ahmedhamdimehdi histopathologicchangesinratorgansuponchronicexposuretoformaldehydevapor AT naliabdulqadrmaaruf histopathologicchangesinratorgansuponchronicexposuretoformaldehydevapor |