Modeling patient-specific adenocarcinoma as spheroids enhances the authenticity of cancer hallmarks and therapeutic susceptibility
Introduction: To help understand and develop treatments for cancer, it is important to have patient-specific, reliable and physiologically-relevant human culture models. Cells from solid tumors have traditionally been grown in 2-dimensional (2D) monolayers, however, it is known that cancer cells can...
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| Main Authors: | Andres S. Espinoza, Rachael N. McVicar, Darren Finlay, Rabi Murad, Kristiina Vuori, Bethany A. Grimmig, Anne Bush, Emily Smith, Thomas Mandel-Clausen, Heather M. McGee, Evan Y. Snyder, Sandra L. Leibel |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-03-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025013581 |
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