An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions
Abstract Oblique lateral interbody fusion (OLIF) is a minimally invasive surgery for the treatment of lumbar degenerative diseases (LDD). Under normal bone mass(NB), supplemental with lateral plate (LP) fixation has been proven to provide stability and reduce complications. However, it is unclear wh...
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Nature Portfolio
2024-11-01
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| Online Access: | https://doi.org/10.1038/s41598-024-80631-8 |
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| author | Zhiqiang Wang Wanzhong Yang Xiaoyin Liu Simin Liang Zecheng Cai Wei Guo Jianqun Zhang Zhaohui Ge |
| author_facet | Zhiqiang Wang Wanzhong Yang Xiaoyin Liu Simin Liang Zecheng Cai Wei Guo Jianqun Zhang Zhaohui Ge |
| author_sort | Zhiqiang Wang |
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| description | Abstract Oblique lateral interbody fusion (OLIF) is a minimally invasive surgery for the treatment of lumbar degenerative diseases (LDD). Under normal bone mass(NB), supplemental with lateral plate (LP) fixation has been proven to provide stability and reduce complications. However, it is unclear whether OLIF combined with LP fixation can achieve satisfactory fixation effects in cases of osteoporosis(OP) or osteopenia (OS)? In this study, Eighteen L3-5 spinal specimens from 3 to 6 months old fresh calves were equally divided into 3 groups: group A (NB), group B (OS) and group C (OP). A load control scheme was adopted and evaluated using multidirectional nondestructive moments (± 7.5 N·m). An electronic universal tester and a tensile/torsion tester were simulated to generate 6 degrees of freedom of motion, and a VIC-3D three-dimensional optical full-field strain measurement system dynamically tracked the surgical segmental displacement. Each spine was evaluated under the following conditions at the L4-5 level: intact (INT); OLIF stand-alone (SA); cage supplemented with LP, cage supplemented with unilateral pedicle screws (UPS), and cage supplemented with bilateral pedicle screws (BPS). The current data show that With NB and OS models, LP fixation significantly reduced ROM in the LB and AR directions, with slightly less stability than BPS fixation and comparable to UPS. In the case of OP, LP fixation may increase the risk of internal fixation failure, and it is more preferable to choose BPS fixation with stronger stability. |
| format | Article |
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| institution | OA Journals |
| issn | 2045-2322 |
| language | English |
| publishDate | 2024-11-01 |
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| spelling | doaj-art-6c5581a96b3945d9958a5dad473ea2402025-08-20T02:08:24ZengNature PortfolioScientific Reports2045-23222024-11-0114111010.1038/s41598-024-80631-8An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditionsZhiqiang Wang0Wanzhong Yang1Xiaoyin Liu2Simin Liang3Zecheng Cai4Wei Guo5Jianqun Zhang6Zhaohui Ge7Department of Orthopaedics, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou City of HenanDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityDepartment of Orthopaedics, General Hospital of Ningxia Medical UniversityAbstract Oblique lateral interbody fusion (OLIF) is a minimally invasive surgery for the treatment of lumbar degenerative diseases (LDD). Under normal bone mass(NB), supplemental with lateral plate (LP) fixation has been proven to provide stability and reduce complications. However, it is unclear whether OLIF combined with LP fixation can achieve satisfactory fixation effects in cases of osteoporosis(OP) or osteopenia (OS)? In this study, Eighteen L3-5 spinal specimens from 3 to 6 months old fresh calves were equally divided into 3 groups: group A (NB), group B (OS) and group C (OP). A load control scheme was adopted and evaluated using multidirectional nondestructive moments (± 7.5 N·m). An electronic universal tester and a tensile/torsion tester were simulated to generate 6 degrees of freedom of motion, and a VIC-3D three-dimensional optical full-field strain measurement system dynamically tracked the surgical segmental displacement. Each spine was evaluated under the following conditions at the L4-5 level: intact (INT); OLIF stand-alone (SA); cage supplemented with LP, cage supplemented with unilateral pedicle screws (UPS), and cage supplemented with bilateral pedicle screws (BPS). The current data show that With NB and OS models, LP fixation significantly reduced ROM in the LB and AR directions, with slightly less stability than BPS fixation and comparable to UPS. In the case of OP, LP fixation may increase the risk of internal fixation failure, and it is more preferable to choose BPS fixation with stronger stability.https://doi.org/10.1038/s41598-024-80631-8OsteoporosisFixationBiomechanicsLateral plate |
| spellingShingle | Zhiqiang Wang Wanzhong Yang Xiaoyin Liu Simin Liang Zecheng Cai Wei Guo Jianqun Zhang Zhaohui Ge An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions Scientific Reports Osteoporosis Fixation Biomechanics Lateral plate |
| title | An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| title_full | An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| title_fullStr | An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| title_full_unstemmed | An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| title_short | An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| title_sort | in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions |
| topic | Osteoporosis Fixation Biomechanics Lateral plate |
| url | https://doi.org/10.1038/s41598-024-80631-8 |
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