Nuclear Magnetic Resonance Fingerprinting and Principal Component Analysis Strategies Lead to Anti-Tuberculosis Natural Product Discovery from Actinomycetes

Nuclear Magnetic Resonance Fingerprinting and Principal Component Analysis Strategies Lead to Anti-Tuberculosis Natural Product Discovery from Actinomycetes

Background: The increasing prevalence of drug-resistant tuberculosis (TB) underscores the urgent need for novel antimicrobial agents. Methods: This study integrates cultivation optimization, nuclear magnetic resonance (NMR) fingerprinting, and principal component analysis (PCA) to explore microbial...

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Bibliographic Details
Main Authors: Jianying Han, Xueting Liu, Lixin Zhang, Ronald J. Quinn, Miaomiao Liu
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antibiotics
Subjects:
tuberculosis
actinomycetes
borrelidin
elaiophylin
polycyclic tetramate macrolactams
bafilomycin
Online Access:https://www.mdpi.com/2079-6382/14/1/108
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