Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Abstract Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Although suppression of macrophage‐derived cytokine p...
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| Main Authors: | Fenghua Zhang, Ehab A Ayaub, Bingbing Wang, Estela Puchulu‐Campanella, Yen‐Hsing Li, Suraj U Hettiarachchi, Spencer D Lindeman, Qian Luo, Sasmita Rout, Madduri Srinivasarao, Abigail Cox, Konstantin Tsoyi, Cheryl Nickerson‐Nutter, Ivan O Rosas, Philip S Low |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2020-06-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.202012034 |
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