Structure-Activity Relationship for Fe(III)-Salen-Like Complexes as Potent Anticancer Agents

Structure-Activity Relationship for Fe(III)-Salen-Like Complexes as Potent Anticancer Agents

Quantitative structure activity relationship (QSAR) for the anticancer activity of Fe(III)-salen and salen-like complexes was studied. The methods of density function theory (B3LYP/LANL2DZ) were used to optimize the structures. A pool of descriptors was calculated: 1497 theoretical descriptors and...

Full description

Saved in:

Bibliographic Details
Main Authors:	Zahra Ghanbari, Mohammad R. Housaindokht, Mohammad Izadyar, Mohammad R. Bozorgmehr, Hossein Eshtiagh-Hosseini, Ahmad R. Bahrami, Maryam M. Matin, Maliheh Javan Khoshkholgh
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/745649
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis, Reductive Reactivity and Anticancer Activity of Cobalt(III)– and Manganese(III)–Salen Complexes
by: Amy Kanina, et al.
Published: (2025-05-01)

[Fe(III)(Salen)Cl] Complex as a Catalyst for the Synthesis of 1, 8-Dioxo-Octahydroxanthene Derivatives
by: H. Khabazzadeh, et al.
Published: (2013-06-01)

Salen–scandium(III) complex-catalyzed asymmetric (3 + 2) annulation of aziridines and aldehydes
by: Linqiang Wang, et al.
Published: (2025-05-01)

Synthesis, Spectral Characterization, and In Vitro Cytotoxicity of Some Fe(III) Complexes Bearing Unsymmetrical Salen-Type Ligands Derived from 2-Hydroxynaphthaldehyde and Substituted Salicylaldehydes
by: Quang Trung Nguyen, et al.
Published: (2021-01-01)

Cobalt-Salen Catalyzed Electroreductive Alkylation of Activated Olefins
by: Sylvie Condon, et al.
Published: (2019-01-01)

Enhanced Corrosion Protection as a Sustainable Approach for Nickel Using Novel FeL Salen Complex: Electrochemical Investigation and DFT Insights
by: Hoda Abd El-Shafy Shilkamy, et al.
Published: (2025-04-01)

Chiral Salen-Based Organic Salts: Synthesis and Potential Antibacterial Activity
by: Marcin Gano, et al.
Published: (2025-05-01)

Utility of Immobilized Metal Salens as Electrocatalysts: Fuel Cells and Organic Electrosynthesis
by: Zachary A. Nguyen, et al.
Published: (2024-12-01)

Hydrogenation of Quinolines and Aldehydes Catalyzed by a Pyrolyzed, Augmented Cobalt-Salen Complex
by: Fabian Schmiedbauer, et al.
Published: (2025-08-01)

Synthesis, characterization, and antibacterial activity of Ni(II) complex bearing salen ligand
by: Mohammed A. Al-Wahish
Published: (2025-08-01)

Investigation of Charge Transfer Complex Formation Between Fe(III) and 2,6-Dihydroxy Benzoic Acid and its Applications for Spectrophotometric Determination of Iron in Aqueous Media
by: Mohammad Saeid Hosseini, et al.
Published: (2009-01-01)

Potent immune-dependent anticancer effects of the non-cardiotoxic anthracycline aclarubicin
by: Giulia Cerrato, et al.
Published: (2025-12-01)

Size Control of Iron Oxide Nanoparticles Using Reverse Microemulsion Method: Morphology, Reduction, and Catalytic Activity in CO Hydrogenation
by: Mohammad Reza Housaindokht, et al.
Published: (2013-01-01)

Novel 3-Ethoxysalicylaldehyde Lanthanide Complexes Obtained by Decomposition of <i>Salen</i>-Type Ligands
by: Paula Mediavilla, et al.
Published: (2025-03-01)

Detection of VOCs and Biogenic Amines Through Luminescent Zn–Salen Complex-Tethered Pyrenyl Arms
by: Roberta Puglisi, et al.
Published: (2024-12-01)

Cyclic Nanostructures of Tungsten Oxide WO3n (n=2–6) as NOx Gas Sensor: A Theoretical Study
by: Mohammad Izadyar, et al.
Published: (2014-01-01)

Magnetization and superparamagnetic behavior of FeCu nanoalloys at room temperature via synthesis and simulation
by: Maryam Bahrami, et al.
Published: (2025-06-01)

Design, theoretical approaches and new framework of pyrazolo[3,4-d]pyrimidine as potent anticancer agents: Efficient synthesis, ADME-T and molecular docking
by: Peduri Suresh Reddy, et al.
Published: (2025-03-01)

A supervised machine-learning analysis of doxorubicin-loaded electrospun nanofibers and their anticancer activity capabilities
by: Mohammadreza Rostami, et al.
Published: (2025-03-01)

Discovery of a selective and reversible LSD1 inhibitor with potent anticancer effects in vitro and in vivo
by: Xiao-Song Zhang, et al.
Published: (2025-12-01)

Current progress in synthetic and medicinal chemistry of pyrazole hybrids as potent anticancer agents with SAR studies
by: Bhupender Nehra, et al.
Published: (2025-06-01)

Synthesis and characterization of innovative GA@Ag-CuO nanocomposite with potent antimicrobial and anticancer properties
by: Amr H. Hashem, et al.
Published: (2025-01-01)

New Silver Complexes with Mixed Thiazolidine and Phosphine Ligands as Highly Potent Antimalarial and Anticancer Agents
by: Nur Rahimah Fitrah Mohd Sofyan, et al.
Published: (2018-01-01)

Development of novel benzamide class I selective lysine deacetylase inhibitors as potent anticancer agents
by: Jason H. Gill, et al.
Published: (2025-12-01)

Fabrication of a multilayer bioabsorbable composite vascular stent utilizing oxidized starch-Fe3O4 nanoparticles and polycaprolactone nanofibers
by: Fatemeh Hataminia, et al.
Published: (2025-03-01)

Evaluation of the Anticancer Effect of Xanthium Strumarium Root Extract on Human Epithelial Ovarian Cancer Cells Using 1H NMR-Based Metabolomics
by: Roya Malekzadeh, et al.
Published: (2020-09-01)

Synthesis, characterization and in silico studies of novel multifunctional imidazole-thiazole hybrids with potent antimicrobial and anticancer properties
by: Deepika Dwarakanath, et al.
Published: (2025-03-01)

Study of Complexes of Tannic Acid with Fe(III) and Fe(II)
by: Zhaofeng Fu, et al.
Published: (2019-01-01)

In vitro evaluation of phytochemical, antioxidant, anti-inflammatory and anticancer properties of Suaeda maritima
by: R. Pavithra, et al.
Published: (2025-06-01)

Productos básicos pequeños de China salen al exterior hacia América Latina: situación actual, dilemas y perspectivas
by: Jia Shihui
Published: (2025-06-01)

<i>Chnoospora minima</i> Polysaccharide-Mediated Green Synthesis of Silver Nanoparticles: Potent Anticancer and Antimicrobial Activities
by: Lakshika Keerthirathna, et al.
Published: (2025-07-01)

Green ZnO nanoparticle synthesis using Tamarindus indica and application as a potent antibacterial and anticancer agent
by: Aarshiya Kwatra, et al.
Published: (2025-06-01)

Biological evaluation of octahydropyrazin[2,1-a:5,4-a′]diisoquinoline derivatives as potent anticancer agents
by: Agnieszka Gornowicz, et al.
Published: (2017-05-01)

Studies on Synthetic and Natural Melanin and Its Affinity for Fe(III) Ion
by: T. G. Costa, et al.
Published: (2012-01-01)

Effect of Acupressure on Anxiety, Stress, and Depression Among the Primary Family Caregivers of the Patients with Stroke
by: Najmeh Javan Sangani, et al.
Published: (2023-03-01)

Clostridium difficile as a potent trigger of colorectal carcinogenesis
by: Javad Nezhadi, et al.
Published: (2025-05-01)

Anticancer and antibacterial activity of the cellulose nanocrystals modified by cyclodextrin and loaded by propolis
by: Maryam Akhondi, et al.
Published: (2025-07-01)

Organic contaminants' bio-degradation with Fe (Ⅲ)
by: TAN Ying-ying, et al.
Published: (2002-05-01)

Design, synthesis, and evaluation of triazolo[1,5-a]pyridines as novel and potent α‑glucosidase inhibitors
by: Fariba Peytam, et al.
Published: (2025-05-01)

Artemisinin-loaded mesoporous silica nanoparticles/electrospun poly(lactic-co-glycolic acid) composite nanofibers for enhanced anticancer efficiency in breast cancer cells
by: Mohammad Eslami Vaghar, et al.
Published: (2024-11-01)