Changes in the tumor microenvironment in recurrent head and neck squamous cell carcinoma and its implication on efficacy of immune checkpoint inhibitors

Changes in the tumor microenvironment in recurrent head and neck squamous cell carcinoma and its implication on efficacy of immune checkpoint inhibitors

Abstract Little is known about changes in the abundance of tumor-infiltrating lymphocytes (TILs) and immune phenotype (IP) in recurrent and/or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). We aimed to compare the TILs and IP between initial and recurrent HNSCCs using paired analysi...

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Main Authors: Dong Hyun Kim, Mingu Kang, Gahee Park, Mohammad Mostafavi, Yoojoo Lim, Chan-Young Ock, Jiwon Koh, Yoon Kyung Jeon, Kyeong Cheon Jung, Soon-Hyun Ahn, Eun-Jae Chung, Seong-Keun Kwon, Bhumsuk Keam
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-024-01504-0
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