Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM

Single-cell view and a novel protective macrophage subset in perivascular adipose tissue in T2DM

Abstract Background Vasculopathy underlies diabetic complications, with perivascular adipose tissue (PVAT) playing crucial roles in its development. However, the changes in the cellular composition and function of PVAT, including the specific cell subsets and mechanisms implicated in type 2 diabetes...

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Main Authors: Jiaxuan Li, Zhenyu Tian, Tongxue Zhang, Jiajia Jin, Xinjie Zhang, Panpan Xie, Haiyan Lin, Junfei Gu, Yingjie Wu, Xiaowei Wang, Shucui Zhang, Xuefang Yan, Dong Guo, Zhe Wang, Qunye Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Diabetes
PVAT
SVF
Single-cell
Pdpn + macrophage
Online Access:https://doi.org/10.1186/s11658-024-00668-5
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