A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation

Actinidia eriantha is one of the species of kiwifruit with a particularly high ascorbic acid (AsA) content. However, the molecular mechanism driving AsA richness in fruit remains unclear. In order to reveal the molecular mechanism of AsA richness in A. eriantha, this study constructed a regulatory n...

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Main Authors: Guang-lian LIAO, Chun-hui HUANG, Dong-feng JIA, Min ZHONG, Jun-jie TAO, Xue-yan QU, Xiao-biao XU
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-11-01
Series:Journal of Integrative Agriculture
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Online Access:http://www.sciencedirect.com/science/article/pii/S2095311923002411
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author Guang-lian LIAO
Chun-hui HUANG
Dong-feng JIA
Min ZHONG
Jun-jie TAO
Xue-yan QU
Xiao-biao XU
author_facet Guang-lian LIAO
Chun-hui HUANG
Dong-feng JIA
Min ZHONG
Jun-jie TAO
Xue-yan QU
Xiao-biao XU
author_sort Guang-lian LIAO
collection DOAJ
description Actinidia eriantha is one of the species of kiwifruit with a particularly high ascorbic acid (AsA) content. However, the molecular mechanism driving AsA richness in fruit remains unclear. In order to reveal the molecular mechanism of AsA richness in A. eriantha, this study constructed a regulatory network related to AsA metabolism by combining genomics, metabolomics and transcriptomics. We assembled a high-quality genome of A. eriantha ‘Ganlv 1’ with only five remaining gaps. The assembly is comprised of 29 pseudochromosomes with a total size of 615.95 Mb, and contig N50 of 20.35 Mb. Among them, 24 of the pseudochromosomes were obtained directly from telomere-to-telomere. The LTR assembly index score and consensus quality value were 21.34 and 39.90%, respectively. Subsequently, 61 metabolites and 2 092 genes were found to be differentially accumulated/expressed during fruit development by metabolome and transcriptome assays, respectively. AsA metabolism and the cyclic regeneration pathway were found to have high expression levels throughout fruit growth and development, suggesting its crucial role in the regulation of AsA. Furthermore, the AsA contents are highly associated with ascorbate peroxidase genes. The genome obtained in this study provides genomic resources for the genetic and breeding research of A. eriantha, and the constructed regulatory network can provide a public data platform for future research on kiwifruit.
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institution Kabale University
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publishDate 2023-11-01
publisher KeAi Communications Co., Ltd.
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spelling doaj-art-6c14a8ba871c4e86bb757a7e2d110f682025-08-20T03:56:23ZengKeAi Communications Co., Ltd.Journal of Integrative Agriculture2095-31192023-11-0122113244325510.1016/j.jia.2023.07.018A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulationGuang-lian LIAO0Chun-hui HUANG1Dong-feng JIA2Min ZHONG3Jun-jie TAO4Xue-yan QU5Xiao-biao XU6Institute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaInstitute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaInstitute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaInstitute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaInstitute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaInstitute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaCorrespondence XU Xiao-biao, Tel/Fax: +86-791-83813586; Institute of Kiwifruit, Jiangxi Agricultural University, Nanchang 330045, P.R.ChinaActinidia eriantha is one of the species of kiwifruit with a particularly high ascorbic acid (AsA) content. However, the molecular mechanism driving AsA richness in fruit remains unclear. In order to reveal the molecular mechanism of AsA richness in A. eriantha, this study constructed a regulatory network related to AsA metabolism by combining genomics, metabolomics and transcriptomics. We assembled a high-quality genome of A. eriantha ‘Ganlv 1’ with only five remaining gaps. The assembly is comprised of 29 pseudochromosomes with a total size of 615.95 Mb, and contig N50 of 20.35 Mb. Among them, 24 of the pseudochromosomes were obtained directly from telomere-to-telomere. The LTR assembly index score and consensus quality value were 21.34 and 39.90%, respectively. Subsequently, 61 metabolites and 2 092 genes were found to be differentially accumulated/expressed during fruit development by metabolome and transcriptome assays, respectively. AsA metabolism and the cyclic regeneration pathway were found to have high expression levels throughout fruit growth and development, suggesting its crucial role in the regulation of AsA. Furthermore, the AsA contents are highly associated with ascorbate peroxidase genes. The genome obtained in this study provides genomic resources for the genetic and breeding research of A. eriantha, and the constructed regulatory network can provide a public data platform for future research on kiwifruit.http://www.sciencedirect.com/science/article/pii/S2095311923002411Actinidia erianthaascorbic acidnon-targeted metabolomegapless genometranscriptome
spellingShingle Guang-lian LIAO
Chun-hui HUANG
Dong-feng JIA
Min ZHONG
Jun-jie TAO
Xue-yan QU
Xiao-biao XU
A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
Journal of Integrative Agriculture
Actinidia eriantha
ascorbic acid
non-targeted metabolome
gapless genome
transcriptome
title A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
title_full A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
title_fullStr A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
title_full_unstemmed A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
title_short A high-quality genome of Actinidia eriantha provides new insight into ascorbic acid regulation
title_sort high quality genome of actinidia eriantha provides new insight into ascorbic acid regulation
topic Actinidia eriantha
ascorbic acid
non-targeted metabolome
gapless genome
transcriptome
url http://www.sciencedirect.com/science/article/pii/S2095311923002411
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