Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams
This study was carried out to investigate the changes occurring in the levels o! serum testosterone in the rams given PGF2u. lurosemid, indomethacin and the combination of this drugs. In the study, 70 Akkaraman rams, approximately 2 years Old were used. PGFa< (0.1, 0.2 and 0.3 mg/kg), furosemid (...
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Selcuk University Press
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| author | İbrahim Pirinçci İzzet Karahan Ferit Gürsu Tanzer Bozkurt Osman Güler |
| author_facet | İbrahim Pirinçci İzzet Karahan Ferit Gürsu Tanzer Bozkurt Osman Güler |
| author_sort | İbrahim Pirinçci |
| collection | DOAJ |
| description | This study was carried out to investigate the changes occurring in the levels o! serum testosterone in the rams given PGF2u. lurosemid, indomethacin and the combination of this drugs. In the study, 70 Akkaraman rams, approximately 2 years Old were used. PGFa< (0.1, 0.2 and 0.3 mg/kg), furosemid (2.0, 4.0 and 6.0 mg/kg), indomethacin (3.0, 6,0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals in one dose and in doses lollowmg on each other's (our days. The bfood samples were collected after drug administrations, Testosterone levels were determined by enzyme immunoassay analyser. The mean testosterone levels in the serum were determined to decrease 641, 528, 382 ng/dl and 507, 343. 317 ng/dl in the rams given in one dose and in doses following on each other's four days PGF2a, according to doses, respectively. On the other hand, it was established to reduce in the mean serum testosterone levels that furosemid also was given in one dose and in doses following on each other's (our days in rams. However, the mean testosterone levels in the serum were determined to increase 926, 953, 993 ng/dl and 950, 1019, 1240 ng/dl in the rams given in one dose and in doses following on each other's four days indomelhacin, respectively. In conclusion. PGF2« and furosemid were defined to decrease the levels of serum testosterone in the rams, depend on lime and doses. In contrast, indomethacin was established to increase the levels of serum testosterone in the rams. |
| format | Article |
| id | doaj-art-6c144400d01047c9aaf66f9ea9358377 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-6c144400d01047c9aaf66f9ea93583772025-01-02T22:36:20ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953172118315Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in ramsİbrahim Pirinçci0İzzet Karahan1Ferit Gürsu2Tanzer Bozkurt3Osman Güler4F.Ü. Veteriner Fakültesi Farmakoloji ve Toksikoloji Aııabilim Dalı, ELAZIĞF.Ü. Veteriner Fakültesi Farmakoloji ve Toksikoloji Aııabilim Dalı, ELAZIĞF.Ü. Tıp Fakültesi, Biyokimya Anabilim Dalı, ELAZIĞF.Ü. Veteriner Fakültesi, Dölerme ve Suni Tohumlama Anabilim Dalı, ELAZIĞT.K. B.lığı Veteriner Kontrol ve Araştırma Enstitüsü, ELAZIĞThis study was carried out to investigate the changes occurring in the levels o! serum testosterone in the rams given PGF2u. lurosemid, indomethacin and the combination of this drugs. In the study, 70 Akkaraman rams, approximately 2 years Old were used. PGFa< (0.1, 0.2 and 0.3 mg/kg), furosemid (2.0, 4.0 and 6.0 mg/kg), indomethacin (3.0, 6,0 and 9,0 mg/kg) and the combinations of these drugs were intramuscularly given the animals in one dose and in doses lollowmg on each other's (our days. The bfood samples were collected after drug administrations, Testosterone levels were determined by enzyme immunoassay analyser. The mean testosterone levels in the serum were determined to decrease 641, 528, 382 ng/dl and 507, 343. 317 ng/dl in the rams given in one dose and in doses following on each other's four days PGF2a, according to doses, respectively. On the other hand, it was established to reduce in the mean serum testosterone levels that furosemid also was given in one dose and in doses following on each other's (our days in rams. However, the mean testosterone levels in the serum were determined to increase 926, 953, 993 ng/dl and 950, 1019, 1240 ng/dl in the rams given in one dose and in doses following on each other's four days indomelhacin, respectively. In conclusion. PGF2« and furosemid were defined to decrease the levels of serum testosterone in the rams, depend on lime and doses. In contrast, indomethacin was established to increase the levels of serum testosterone in the rams.http://eurasianjvetsci.org/pdf.php3?id=315prostaglandin f2αfurosemidindomethacintestosterone |
| spellingShingle | İbrahim Pirinçci İzzet Karahan Ferit Gürsu Tanzer Bozkurt Osman Güler Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams Eurasian Journal of Veterinary Sciences prostaglandin f2α furosemid indomethacin testosterone |
| title | Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams |
| title_full | Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams |
| title_fullStr | Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams |
| title_full_unstemmed | Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams |
| title_short | Investigation of the effcets of prostaglandin f2α, furosenıid and indomethacin on testosterone levels in rams |
| title_sort | investigation of the effcets of prostaglandin f2 945 furoseniid and indomethacin on testosterone levels in rams |
| topic | prostaglandin f2α furosemid indomethacin testosterone |
| url | http://eurasianjvetsci.org/pdf.php3?id=315 |
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