Molecular Diagnosis In Infectious Keratitis
Microbial keratitis is a very important public health problem in our country. The magnitude of the burden of this problem is not often fully understood and hence it is often termed as a “silent epidemic”. The affected population are often the vulnerable members of the society like people working in...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-04-01
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| Series: | Delhi Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.7869/djo.55 |
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| author | Venkatesh Prajna N Lokeshwari A Lalitha Prajna |
| author_facet | Venkatesh Prajna N Lokeshwari A Lalitha Prajna |
| author_sort | Venkatesh Prajna N |
| collection | DOAJ |
| description | Microbial keratitis is a very important public health problem in our country. The magnitude of the burden of this problem is not often fully understood and hence it is often termed as a “silent epidemic”. The affected population are often the vulnerable members of the society like people working in fields, warehouses and manual unskilled labour intensive activities. Very often, these affected individuals delay their presentation to an ophthalmologist and often indulge in self medications. Even though classic clinical features have been described for various aetiological organisms causing keratitis, it is extremely difficult to accurately predict the same by clinical examination alone. Microbiological support systems are extremely important and mandatory for diagnosing and ultimately treating this problem. While routine microbiological investigations like smears and cultures remain the backbone of the armamentarium, newer molecular tests such as polymerase chain reaction (PCR) tests are useful in certain indications. These tests are useful to detect slow growing organisms, fastidious organisms and may offer a comparative quick diagnosis. This review offers the current applications of the use of these molecular tests with reference to suppurative microbial keratitis. |
| format | Article |
| id | doaj-art-6c09df20e68644d288f576c3b301fccf |
| institution | DOAJ |
| issn | 0972-0200 2454-2784 |
| language | English |
| publishDate | 2014-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delhi Journal of Ophthalmology |
| spelling | doaj-art-6c09df20e68644d288f576c3b301fccf2025-08-20T03:11:07ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842014-04-0124425826210.7869/djo.55Molecular Diagnosis In Infectious KeratitisVenkatesh Prajna NLokeshwari ALalitha PrajnaMicrobial keratitis is a very important public health problem in our country. The magnitude of the burden of this problem is not often fully understood and hence it is often termed as a “silent epidemic”. The affected population are often the vulnerable members of the society like people working in fields, warehouses and manual unskilled labour intensive activities. Very often, these affected individuals delay their presentation to an ophthalmologist and often indulge in self medications. Even though classic clinical features have been described for various aetiological organisms causing keratitis, it is extremely difficult to accurately predict the same by clinical examination alone. Microbiological support systems are extremely important and mandatory for diagnosing and ultimately treating this problem. While routine microbiological investigations like smears and cultures remain the backbone of the armamentarium, newer molecular tests such as polymerase chain reaction (PCR) tests are useful in certain indications. These tests are useful to detect slow growing organisms, fastidious organisms and may offer a comparative quick diagnosis. This review offers the current applications of the use of these molecular tests with reference to suppurative microbial keratitis.https://journals.lww.com/10.7869/djo.55pcrpolymerase chain reactionmolecular diagnosis |
| spellingShingle | Venkatesh Prajna N Lokeshwari A Lalitha Prajna Molecular Diagnosis In Infectious Keratitis Delhi Journal of Ophthalmology pcr polymerase chain reaction molecular diagnosis |
| title | Molecular Diagnosis In Infectious Keratitis |
| title_full | Molecular Diagnosis In Infectious Keratitis |
| title_fullStr | Molecular Diagnosis In Infectious Keratitis |
| title_full_unstemmed | Molecular Diagnosis In Infectious Keratitis |
| title_short | Molecular Diagnosis In Infectious Keratitis |
| title_sort | molecular diagnosis in infectious keratitis |
| topic | pcr polymerase chain reaction molecular diagnosis |
| url | https://journals.lww.com/10.7869/djo.55 |
| work_keys_str_mv | AT venkateshprajnan moleculardiagnosisininfectiouskeratitis AT lokeshwaria moleculardiagnosisininfectiouskeratitis AT lalithaprajna moleculardiagnosisininfectiouskeratitis |