Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis

Short-term and long-term oncological outcomes of chemoradiotherapy for rectal cancer patients with or without oxaliplatin: a propensity score-matched retrospective analysis

Abstract Background/Aim Current approaches for locally advanced rectal cancer (LARC) typically recommend neoadjuvant chemoradiotherapy (nCRT) with 5-fluorouracil (5FU) or its oral analogs followed by surgery as the standard of care. However, the question of whether intensifying concurrent chemothera...

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Main Authors: Amirali Azimi, Fatemeh Sadat Tabatabaei, Kasra Kolahdouzan, Hamideh Rashidian, Forouzan Nourbakhsh, Maryam Abedini Parizi, Nima Mousavi Darzikolaee, Reyhaneh Bayani, Samaneh Salarvand, Azadeh Sharifian, Farzaneh Bagheri, Saeed Rezaei, Naeim Nabian, Reza Nazari, Negin Mohammadi, Mohammad Babaei, Marzieh Lashkari, Farshid Farhan, Mahdi Aghili, Felipe Couñago, Maria Antonietta Gambacorta, Reza Ghalehtaki
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Radiation Oncology
Subjects:
Rectal cancer
Oxaliplatin
Radiotherapy
Survival
Neoadjuvant therapy
Online Access:https://doi.org/10.1186/s13014-024-02562-y
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