Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese
Reproductive traits are important economic traits in goose production, and geese's reproductive ability directly affects goose farms' economic benefits. In this study, we selected 240 Yili females goose in the egg-laying stage to construct a test population and measured the individual egg-...
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| Language: | English |
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Elsevier
2025-06-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579125003669 |
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| author | Xiaoyu Zhao Zhiyong Mei Haiying Li Yingping Wu Lu Pan Yan Cao |
| author_facet | Xiaoyu Zhao Zhiyong Mei Haiying Li Yingping Wu Lu Pan Yan Cao |
| author_sort | Xiaoyu Zhao |
| collection | DOAJ |
| description | Reproductive traits are important economic traits in goose production, and geese's reproductive ability directly affects goose farms' economic benefits. In this study, we selected 240 Yili females goose in the egg-laying stage to construct a test population and measured the individual egg-laying performance and hatching performance of Yili females goose. Based on the above phenotypic data, we conducted genome-wide linkage analysis for five indicators of reproductive traits of Yili geese (egg-laying capacity, fertilization rate, hatching rate, egg weight, and egg shape) to screen candidate genes. Genome-wide association analysis of reproductive traits in Yili geese was performed by resequencing, and a total of 1 single nucleotide polymorphism (SNP) were screened for significant association with hatchability, 34 SNPs were screened for potential association with egg production, egg weight, egg shape, and fertilisation rate, and 35 candidate genes were screened for association with egg production, egg weight, egg shape and fertilization rate in the vicinity of these loci across the whole genome. 35 candidate genes were screened near these loci. Through bioinformatics analysis, genes such as carbonic anhydrase 2 (CA2), very low density lipoprotein receptor (VLDLR), HMG-box transcription factor 1 (HBP1), and transient receptor potential cation channel subfamily M member 5 (TRPM5) were obtained to be closely related to calcium deposition, follicular development, embryonic development, and estrogen secretion level. These genes can be used as candidate genes affecting the reproductive performance of Yili geese. This study provides a reference basis for further analysis of the molecular regulation mechanism of goose reproductive performance and enriches the theory of genetic regulation of goose reproductive performance. |
| format | Article |
| id | doaj-art-6bf4a2ca9fd64d72907bf6e98aeb1880 |
| institution | OA Journals |
| issn | 0032-5791 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
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| series | Poultry Science |
| spelling | doaj-art-6bf4a2ca9fd64d72907bf6e98aeb18802025-08-20T02:32:23ZengElsevierPoultry Science0032-57912025-06-01104610512710.1016/j.psj.2025.105127Genome-wide association study and candidate gene analysis of reproductive traits in Yili geeseXiaoyu Zhao0Zhiyong Mei1Haiying Li2Yingping Wu3Lu Pan4Yan Cao5College of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaCollege of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaCorrespondence author at. College of Animal Scienc, Xinjiang Agricultural University, Genetics and Molecular Biology, No.311 Nongda East Road, Urumqi, PR China.; College of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaCollege of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaCollege of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaCollege of Animal Scienc, Xinjiang Agricultural University, Urumqi, PR ChinaReproductive traits are important economic traits in goose production, and geese's reproductive ability directly affects goose farms' economic benefits. In this study, we selected 240 Yili females goose in the egg-laying stage to construct a test population and measured the individual egg-laying performance and hatching performance of Yili females goose. Based on the above phenotypic data, we conducted genome-wide linkage analysis for five indicators of reproductive traits of Yili geese (egg-laying capacity, fertilization rate, hatching rate, egg weight, and egg shape) to screen candidate genes. Genome-wide association analysis of reproductive traits in Yili geese was performed by resequencing, and a total of 1 single nucleotide polymorphism (SNP) were screened for significant association with hatchability, 34 SNPs were screened for potential association with egg production, egg weight, egg shape, and fertilisation rate, and 35 candidate genes were screened for association with egg production, egg weight, egg shape and fertilization rate in the vicinity of these loci across the whole genome. 35 candidate genes were screened near these loci. Through bioinformatics analysis, genes such as carbonic anhydrase 2 (CA2), very low density lipoprotein receptor (VLDLR), HMG-box transcription factor 1 (HBP1), and transient receptor potential cation channel subfamily M member 5 (TRPM5) were obtained to be closely related to calcium deposition, follicular development, embryonic development, and estrogen secretion level. These genes can be used as candidate genes affecting the reproductive performance of Yili geese. This study provides a reference basis for further analysis of the molecular regulation mechanism of goose reproductive performance and enriches the theory of genetic regulation of goose reproductive performance.http://www.sciencedirect.com/science/article/pii/S0032579125003669Yili geeseEgg productionHatchabilityGWAS |
| spellingShingle | Xiaoyu Zhao Zhiyong Mei Haiying Li Yingping Wu Lu Pan Yan Cao Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese Poultry Science Yili geese Egg production Hatchability GWAS |
| title | Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese |
| title_full | Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese |
| title_fullStr | Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese |
| title_full_unstemmed | Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese |
| title_short | Genome-wide association study and candidate gene analysis of reproductive traits in Yili geese |
| title_sort | genome wide association study and candidate gene analysis of reproductive traits in yili geese |
| topic | Yili geese Egg production Hatchability GWAS |
| url | http://www.sciencedirect.com/science/article/pii/S0032579125003669 |
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