A Mendelian randomization study of the gut microbiota and risk of knee osteoarthritis and the mediating role of immune cells

Abstract With increasing research on the gut microbiota (GM), there is growing evidence suggesting that GM may influence the risk of knee osteoarthritis (KOA) by modulating immune cell activity. However, the causal relationship between GM, immune cells, and KOA has not been thoroughly investigated....

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Bibliographic Details
Main Authors: Jiayu Zhang, Xiuyue Qiu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-14007-x
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