SEgene identifies links between super enhancers and gene expression across cell types
Abstract Enhancers are non-coding DNA regions that facilitate gene transcription, with a specialized subset, super-enhancers, known to exert exceptionally strong transcriptional activation effects. Super-enhancers have been implicated in oncogenesis, and their identification is achievable through hi...
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| Main Authors: | Norio Shinkai, Ken Asada, Hidenori Machino, Ken Takasawa, Satoshi Takahashi, Nobuji Kouno, Masaaki Komatsu, Ryuji Hamamoto, Syuzo Kaneko |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | npj Systems Biology and Applications |
| Online Access: | https://doi.org/10.1038/s41540-025-00533-x |
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