Multi-omics analysis of bidirectional liquid–liquid phase separation signatures reveals immunotherapy response and prognosis in renal cell carcinoma
Highlights Mendelian randomization screening of renal cell carcinoma-associated LLPS genes; A Bidirectional Liquid-Liquid Phase Separation-associated Index (B-LLPSI) based on GPRIN1, TTK and DTL was developed for the prediction of immunotherapy efficacy and prognosis in renal clear cell carcinoma pa...
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| Main Authors: | Zheyu Wang, Hongze Li, Xiaolong Hou, Senyu Zhang, Kai Deng, Nianqiang Wang, Wei Wang, Yuyan Zhu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-025-14749-x |
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